Basophilic erythroblast

These images show examples of basophilic erythroblasts, the first stage of erythropoiesis that is easily identifiable. These cells are generated by mitotic division from proerythroblasts. The cytoplasm of the basophilic erythroblasts is strongly basophilic resulting from the numerous polyribosomes that are synthesizing hemoglobin. The large nucleus typically possesses a “checker-board” chromatin pattern that is typical of differentiating erythrocytes. 1000x, 1000x