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Neutrophilic myelocyte and metamyelocyte
Neutrophilic myelocytes are the first definitive cell type in the neutrophilic lineage. At this stage, the cells begin to synthesize neutrophil-specific granules, which then come to predominate since azurophilic granules are no longer being produced. The spherical nucleus of neutrophilic myelocytes develops a distinct indentation at which point they become metamyelocytes. 1000x all
![Neutrophilic myelocyte <p>Neutrophilic myelocytes are the first definitive cell type in the neutrophilic lineage. At this stage, the cells begin to synthesize neutrophil-specific granules, which then come to predominate since azurophilic granules are no longer being produced. The spherical nucleus of neutrophilic myelocytes develops a distinct indentation at which point they become metamyelocytes. 1000x all</p>](https://digitalhistology.org/wp-content/uploads/2018/01/Or.CV_.Hemo-11-1-ping.png)
Neutrophilic myelocyte
Neutrophilic myelocytes are the first definitive cell type in the neutrophilic lineage. At this stage, the cells begin to synthesize neutrophil-specific granules, which then come to predominate since azurophilic granules are no longer being produced. The spherical nucleus of neutrophilic myelocytes develops a distinct indentation at which point they become metamyelocytes. 1000x all
![Neutrophilic metamyelocytes <p>Neutrophilic myelocytes are the first definitive cell type in the neutrophilic lineage. At this stage, the cells begin to synthesize neutrophil-specific granules, which then come to predominate since azurophilic granules are no longer being produced. The spherical nucleus of neutrophilic myelocytes develops a distinct indentation at which point they become metamyelocytes. 1000x all</p>](https://digitalhistology.org/wp-content/uploads/2018/01/Or.CV_.Hemo-11-2-ping.png)
Neutrophilic metamyelocytes
Neutrophilic myelocytes are the first definitive cell type in the neutrophilic lineage. At this stage, the cells begin to synthesize neutrophil-specific granules, which then come to predominate since azurophilic granules are no longer being produced. The spherical nucleus of neutrophilic myelocytes develops a distinct indentation at which point they become metamyelocytes. 1000x all
![Nuclei <p>Neutrophilic myelocytes are the first definitive cell type in the neutrophilic lineage. At this stage, the cells begin to synthesize neutrophil-specific granules, which then come to predominate since azurophilic granules are no longer being produced. The spherical nucleus of neutrophilic myelocytes develops a distinct indentation at which point they become metamyelocytes. 1000x all</p>](https://digitalhistology.org/wp-content/uploads/2018/01/Or.CV_.Hemo-11-3-ping.png)
Nuclei
Neutrophilic myelocytes are the first definitive cell type in the neutrophilic lineage. At this stage, the cells begin to synthesize neutrophil-specific granules, which then come to predominate since azurophilic granules are no longer being produced. The spherical nucleus of neutrophilic myelocytes develops a distinct indentation at which point they become metamyelocytes. 1000x all
![Granules > <p>Specific, or secondary, granules in neutrophils contain a variety of proteins including collagenase and lysozyme, enzymes important for migration and destruction of phagocytosed bacteria. Azurophilic (primary) granules, lysosomes, are a nonspecific, granule present in all granulocytes, monocytes and platelets. Specific granules are unique to a single type of granulocyte.</p>](https://digitalhistology.org/wp-content/uploads/2018/01/Or.CV_.Hemo-11-4-ping.png)
Granules >
Specific, or secondary, granules in neutrophils contain a variety of proteins including collagenase and lysozyme, enzymes important for migration and destruction of phagocytosed bacteria. Azurophilic (primary) granules, lysosomes, are a nonspecific, granule present in all granulocytes, monocytes and platelets. Specific granules are unique to a single type of granulocyte.