Neutrophilic myelocyte and metamyelocyte

Neutrophilic myelocytes are the first definitive cell type in the neutrophilic lineage. At this stage, the cells begin to synthesize neutrophil-specific granules, which then come to predominate since azurophilic granules are no longer being produced. The spherical nucleus of neutrophilic myelocytes develops a distinct indentation at which point they become metamyelocytes. 1000x all

Neutrophilic myelocytes are the first definitive cell type in the neutrophilic lineage. At this stage, the cells begin to synthesize neutrophil-specific granules, which then come to predominate since azurophilic granules are no longer being produced. The spherical nucleus of neutrophilic myelocytes develops a distinct indentation at which point they become metamyelocytes. 1000x all

Neutrophilic myelocytes are the first definitive cell type in the neutrophilic lineage. At this stage, the cells begin to synthesize neutrophil-specific granules, which then come to predominate since azurophilic granules are no longer being produced. The spherical nucleus of neutrophilic myelocytes develops a distinct indentation at which point they become metamyelocytes. 1000x all

Specific, or secondary, granules in neutrophils contain a variety of proteins including collagenase and lysozyme, enzymes important for migration and destruction of phagocytosed bacteria. Azurophilic (primary) granules, lysosomes, are a nonspecific, granule present in all granulocytes, monocytes and platelets.  Specific granules are unique to a single type of granulocyte.