Stratum spinosum
Keratinocytes of stratum spinosum are firmly attached to each other by numerous desmosomes, which anchor the cells against physical abrasion. Desmosomes are associated with large numbers of tonofibrils that extend into the cytoplasm. The presence of these desmosomes produces the spiny appearance of stratum spinosum. 6000x
Keratinocyte nuclei
Keratinocytes of stratum spinosum are firmly attached to each other by numerous desmosomes, which anchor the cells against physical abrasion. Desmosomes are associated with large numbers of tonofibrils that extend into the cytoplasm. The presence of these desmosomes produces the spiny appearance of stratum spinosum. 6000x
Plasma membrane
Keratinocytes of stratum spinosum are firmly attached to each other by numerous desmosomes, which anchor the cells against physical abrasion. Desmosomes are associated with large numbers of tonofibrils that extend into the cytoplasm. The presence of these desmosomes produces the spiny appearance of stratum spinosum. 6000x
Desmosomes
Keratinocytes of stratum spinosum are firmly attached to each other by numerous desmosomes, which anchor the cells against physical abrasion. Desmosomes are associated with large numbers of tonofibrils that extend into the cytoplasm. The presence of these desmosomes produces the spiny appearance of stratum spinosum. 6000x
Tonofibrils
Keratinocytes of stratum spinosum are firmly attached to each other by numerous desmosomes, which anchor the cells against physical abrasion. Desmosomes are associated with large numbers of tonofibrils that extend into the cytoplasm. The presence of these desmosomes produces the spiny appearance of stratum spinosum. 6000x