
Stratum spinosum
Stratum spinosum contains 3-10 layers of polygonal keratinocytes with euchromatic nuclei. These cells possess prominent bundles of intermediate filaments (tonofibrils) containing keratin tonofilaments. Adjacent keratinocytes are attached by numerous desmosomes, creating the spiny appearance around their periphery. 200x, 2000x

Stratum spinosum cells
Stratum spinosum contains 3-10 layers of polygonal keratinocytes with euchromatic nuclei. These cells possess prominent bundles of intermediate filaments (tonofibrils) containing keratin tonofilaments. Adjacent keratinocytes are attached by numerous desmosomes, creating the spiny appearance around their periphery. 200x, 2000x

- Tonofibrils
Stratum spinosum contains 3-10 layers of polygonal keratinocytes with euchromatic nuclei. These cells possess prominent bundles of intermediate filaments (tonofibrils) containing keratin tonofilaments. Adjacent keratinocytes are attached by numerous desmosomes, creating the spiny appearance around their periphery. 200x, 2000x