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Placenta: 3rd trimester
Villi appear similar to those in the early placenta except that fetal connective tissue is more condensed; cytotrophoblast cells form a discontinuous layer beneath the syncytiotrophoblast; fibrinoid is seen in villi; and syncytiotrophoblastic nuclei tend to clump. Fetal capillaries are more numerous and are frequently located immediately beneath the syncytial layer. 400x

Intervillous space
Villi appear similar to those in the early placenta except that fetal connective tissue is more condensed; cytotrophoblast cells form a discontinuous layer beneath the syncytiotrophoblast; fibrinoid is seen in villi; and syncytiotrophoblastic nuclei tend to clump. Fetal capillaries are more numerous and are frequently located immediately beneath the syncytial layer. 400x

Floating villi
Villi appear similar to those in the early placenta except that fetal connective tissue is more condensed; cytotrophoblast cells form a discontinuous layer beneath the syncytiotrophoblast; fibrinoid is seen in villi; and syncytiotrophoblastic nuclei tend to clump. Fetal capillaries are more numerous and are frequently located immediately beneath the syncytial layer. 400x

- Fetal connective tissue
Villi appear similar to those in the early placenta except that fetal connective tissue is more condensed; cytotrophoblast cells form a discontinuous layer beneath the syncytiotrophoblast; fibrinoid is seen in villi; and syncytiotrophoblastic nuclei tend to clump. Fetal capillaries are more numerous and are frequently located immediately beneath the syncytial layer. 400x

- Fetal blood vessels
Villi appear similar to those in the early placenta except that fetal connective tissue is more condensed; cytotrophoblast cells form a discontinuous layer beneath the syncytiotrophoblast; fibrinoid is seen in villi; and syncytiotrophoblastic nuclei tend to clump. Fetal capillaries are more numerous and are frequently located immediately beneath the syncytial layer. 400x

- Cytotrophoblast
Villi appear similar to those in the early placenta except that fetal connective tissue is more condensed; cytotrophoblast cells form a discontinuous layer beneath the syncytiotrophoblast; fibrinoid is seen in villi; and syncytiotrophoblastic nuclei tend to clump. Fetal capillaries are more numerous and are frequently located immediately beneath the syncytial layer. 400x

- Syncytiotrophoblast
Villi appear similar to those in early placenta except that fetal connective tissue is more condensed; cytotrophoblast cells form a discontinuous layer beneath the syncytiotrophoblast; fibrinoid is seen in villi; and syncytiotrophoblastic nuclei tend to clump. Fetal capillaries are more numerous and are frequently located immediately beneath the syncytial layer. 400x

- Clumped nuclei
Villi appear similar to those in the early placenta except that fetal connective tissue is more condensed; cytotrophoblast cells form a discontinuous layer beneath the syncytiotrophoblast; fibrinoid is seen in villi; and syncytiotrophoblastic nuclei tend to clump. Fetal capillaries are more numerous and are frequently located immediately beneath the syncytial layer. 400x

- Fibrinoid
Villi appear similar to those in the early placenta except that fetal connective tissue is more condensed; cytotrophoblast cells form a discontinuous layer beneath the syncytiotrophoblast; fibrinoid is seen in villi; and syncytiotrophoblastic nuclei tend to clump. Fetal capillaries are more numerous and are frequently located immediately beneath the syncytial layer. 400x