![This is blank.](https://digitalhistology.org/wp-content/themes/histology-unified/imgs/trans.png)
Lymph node
This low magnification image of a lymph node shows the distinct histology of the cortex and medulla. The section also includes a large portion of the hilum. Due to the plane of section, a portion of the cortex appears disconnected, separated by a portion of the hilum. The node is surrounded by adipose tissue. 40x
![Cortex > <p>The outer cortex (superficial cortex, nodular cortex) contains lymphoid nodules that are populated mostly by B lymphocytes. The inner paracortex (deep cortex) resembles diffuse lymphoid tissue and is populated mostly by T lymphocytes.</p>](https://digitalhistology.org/wp-content/uploads/2017/11/Or.Ly_.Node-3-1-ping.png)
Cortex >
The outer cortex (superficial cortex, nodular cortex) contains lymphoid nodules that are populated mostly by B lymphocytes. The inner paracortex (deep cortex) resembles diffuse lymphoid tissue and is populated mostly by T lymphocytes.
![- Outer cortex <p>The outer cortex (superficial cortex, nodular cortex) contains lymphoid nodules that are populated mostly by B lymphocytes. The inner paracortex (deep cortex) resembles diffuse lymphoid tissue and is populated mostly by T lymphocytes.</p>](https://digitalhistology.org/wp-content/uploads/2017/11/Or.Ly_.Node-3-2-ping.png)
- Outer cortex
The outer cortex (superficial cortex, nodular cortex) contains lymphoid nodules that are populated mostly by B lymphocytes. The inner paracortex (deep cortex) resembles diffuse lymphoid tissue and is populated mostly by T lymphocytes.
![- Deep cortex (paracortex) <p>The outer cortex (superficial cortex, nodular cortex) contains lymphoid nodules that are populated mostly by B lymphocytes. The inner paracortex (deep cortex) resembles diffuse lymphoid tissue and is populated mostly by T lymphocytes.</p>](https://digitalhistology.org/wp-content/uploads/2017/11/Or.Ly_.Node-3-3-ping.png)
- Deep cortex (paracortex)
The outer cortex (superficial cortex, nodular cortex) contains lymphoid nodules that are populated mostly by B lymphocytes. The inner paracortex (deep cortex) resembles diffuse lymphoid tissue and is populated mostly by T lymphocytes.
![- Lymphoid nodules <p>The outer cortex (superficial cortex, nodular cortex) contains lymphoid nodules that are populated mostly by B lymphocytes. The inner paracortex (deep cortex) resembles diffuse lymphoid tissue and is populated mostly by T lymphocytes.</p>](https://digitalhistology.org/wp-content/uploads/2017/11/Or.Ly_.Node-3-4-ping.png)
- Lymphoid nodules
The outer cortex (superficial cortex, nodular cortex) contains lymphoid nodules that are populated mostly by B lymphocytes. The inner paracortex (deep cortex) resembles diffuse lymphoid tissue and is populated mostly by T lymphocytes.
![Medulla > <p>The medulla consists of a series of medullary cords (B-dependent areas), that are finger-like projections of lymphoid tissue. Between the cords are large channels, called medullary sinuses, that receive lymph from the cortical sinuses. The medullary sinuses contain large numbers of lymphocytes.</p>](https://digitalhistology.org/wp-content/uploads/2017/11/Or.Ly_.Node-3-5-ping.png)
Medulla >
The medulla consists of a series of medullary cords (B-dependent areas), that are finger-like projections of lymphoid tissue. Between the cords are large channels, called medullary sinuses, that receive lymph from the cortical sinuses. The medullary sinuses contain large numbers of lymphocytes.
![- Medullary cords <p>The medulla consists of a series of medullary cords (B-dependent areas), that are finger-like projections of lymphoid tissue. Between the cords are large channels, called medullary sinuses, that receive lymph from the cortical sinuses. The medullary sinuses contain large numbers of lymphocytes.</p>](https://digitalhistology.org/wp-content/uploads/2017/11/Or.Ly_.Node-3-6-ping.png)
- Medullary cords
The medulla consists of a series of medullary cords (B-dependent areas), that are finger-like projections of lymphoid tissue. Between the cords are large channels, called medullary sinuses, that receive lymph from the cortical sinuses. The medullary sinuses contain large numbers of lymphocytes.
![- Medullary sinuses <p>The medulla consists of a series of medullary cords (B-dependent areas), that are finger-like projections of lymphoid tissue. Between the cords are large channels, called medullary sinuses, that receive lymph from the cortical sinuses. The medullary sinuses contain large numbers of lymphocytes.</p>](https://digitalhistology.org/wp-content/uploads/2017/11/Or.Ly_.Node-3-7-ping.png)
- Medullary sinuses
The medulla consists of a series of medullary cords (B-dependent areas), that are finger-like projections of lymphoid tissue. Between the cords are large channels, called medullary sinuses, that receive lymph from the cortical sinuses. The medullary sinuses contain large numbers of lymphocytes.
![Hilum > <p>The hilum is the indented portion of lymph nodes where efferent lymphatics and venules exit and where arterioles enter. The hilum contains a network of anastomosing efferent vessels that receive lymph passing through the medullary sinuses. Filling the hilum is supporting connective tissue and adipose tissue.</p>](https://digitalhistology.org/wp-content/uploads/2017/11/Or.Ly_.Node-3-8-ping.png)
Hilum >
The hilum is the indented portion of lymph nodes where efferent lymphatics and venules exit and where arterioles enter. The hilum contains a network of anastomosing efferent vessels that receive lymph passing through the medullary sinuses. Filling the hilum is supporting connective tissue and adipose tissue.
![Efferent lymphatics <p>The hilum is the indented portion of lymph nodes where the efferent lymphatics and venules exit and where arterioles enter. The hilum contains a network of anastomosing efferent vessels that receive the lymph passing through the medullary sinuses. Filling the hilum is supporting connective tissue and adipose tissue.</p>](https://digitalhistology.org/wp-content/uploads/2017/11/Or.Ly_.Node-3-9-ping.png)
Efferent lymphatics
The hilum is the indented portion of lymph nodes where the efferent lymphatics and venules exit and where arterioles enter. The hilum contains a network of anastomosing efferent vessels that receive the lymph passing through the medullary sinuses. Filling the hilum is supporting connective tissue and adipose tissue.
![Blood vessels <p>The hilum is the indented portion of lymph nodes where the efferent lymphatics and venules exit and where arterioles enter. The hilum contains a network of anastomosing efferent vessels that receive the lymph passing through the medullary sinuses. Filling the hilum is supporting connective tissue and adipose tissue.</p>](https://digitalhistology.org/wp-content/uploads/2017/11/Or.Ly_.Node-3-10-ping.png)
Blood vessels
The hilum is the indented portion of lymph nodes where the efferent lymphatics and venules exit and where arterioles enter. The hilum contains a network of anastomosing efferent vessels that receive the lymph passing through the medullary sinuses. Filling the hilum is supporting connective tissue and adipose tissue.
![Image source > <p>Image taken of a slide from the University of Michigan collection.</p>](https://digitalhistology.org/wp-content/uploads/2017/11/Or.Ly_.Node-3-11-ping.png)
Image source >
Image taken of a slide from the University of Michigan collection.