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Liver
The classic liver lobule is more clearly demarcated by connective tissue in a pig than in the human. Blood enters the liver in the hepatic portal vein or hepatic artery; branches of both vessels are located in a portal canal. From these branches, blood enters hepatic sinusoids between plates of hepatocytes and is carried into the central vein. Bile is produced by the hepatocytes and flows in bile canaliculi toward the periphery of the lobule where it enters branches of the bile duct. 100x
![Liver lobule <p>The classic liver lobule is more clearly demarcated by connective tissue in a pig than in the human. Blood enters the liver in the hepatic portal vein or hepatic artery; branches of both vessels are located in a portal canal. From these branches, blood enters hepatic sinusoids between plates of hepatocytes and is carried into the central vein. Bile is produced by the hepatocytes and flows in bile canaliculi toward the periphery of the lobule where it enters branches of the bile duct. 100x</p>](https://digitalhistology.org/wp-content/uploads/2017/10/Or.Dig_.MajGl_.Liv-2-1-ping.png)
Liver lobule
The classic liver lobule is more clearly demarcated by connective tissue in a pig than in the human. Blood enters the liver in the hepatic portal vein or hepatic artery; branches of both vessels are located in a portal canal. From these branches, blood enters hepatic sinusoids between plates of hepatocytes and is carried into the central vein. Bile is produced by the hepatocytes and flows in bile canaliculi toward the periphery of the lobule where it enters branches of the bile duct. 100x
![Portal canals <p>The classic liver lobule is more clearly demarcated by connective tissue in a pig than in the human. Blood enters the liver in the hepatic portal vein or hepatic artery; branches of both vessels are located in a portal canal. From these branches, blood enters hepatic sinusoids between plates of hepatocytes and is carried into the central vein. Bile is produced by the hepatocytes and flows in bile canaliculi toward the periphery of the lobule where it enters branches of the bile duct. 100x</p>](https://digitalhistology.org/wp-content/uploads/2017/10/Or.Dig_.MajGl_.Liv-2-2-ping.png)
Portal canals
The classic liver lobule is more clearly demarcated by connective tissue in a pig than in the human. Blood enters the liver in the hepatic portal vein or hepatic artery; branches of both vessels are located in a portal canal. From these branches, blood enters hepatic sinusoids between plates of hepatocytes and is carried into the central vein. Bile is produced by the hepatocytes and flows in bile canaliculi toward the periphery of the lobule where it enters branches of the bile duct. 100x
![Central veins <p>The classic liver lobule is more clearly demarcated by connective tissue in a pig than in the human. Blood enters the liver in the hepatic portal vein or hepatic artery; branches of both vessels are located in a portal canal. From these branches, blood enters hepatic sinusoids between plates of hepatocytes and is carried into the central vein. Bile is produced by the hepatocytes and flows in bile canaliculi toward the periphery of the lobule where it enters branches of the bile duct. 100x</p>](https://digitalhistology.org/wp-content/uploads/2017/10/Or.Dig_.MajGl_.Liv-2-3-ping.png)
Central veins
The classic liver lobule is more clearly demarcated by connective tissue in a pig than in the human. Blood enters the liver in the hepatic portal vein or hepatic artery; branches of both vessels are located in a portal canal. From these branches, blood enters hepatic sinusoids between plates of hepatocytes and is carried into the central vein. Bile is produced by the hepatocytes and flows in bile canaliculi toward the periphery of the lobule where it enters branches of the bile duct. 100x
![Sinusoids <p>The classic liver lobule is more clearly demarcated by connective tissue in a pig than in the human. Blood enters the liver in the hepatic portal vein or hepatic artery; branches of both vessels are located in a portal canal. From these branches, blood enters hepatic sinusoids between plates of hepatocytes and is carried into the central vein. Bile is produced by the hepatocytes and flows in bile canaliculi toward the periphery of the lobule where it enters branches of the bile duct. 100x</p>](https://digitalhistology.org/wp-content/uploads/2017/10/Or.Dig_.MajGl_.Liv-2-4-ping.png)
Sinusoids
The classic liver lobule is more clearly demarcated by connective tissue in a pig than in the human. Blood enters the liver in the hepatic portal vein or hepatic artery; branches of both vessels are located in a portal canal. From these branches, blood enters hepatic sinusoids between plates of hepatocytes and is carried into the central vein. Bile is produced by the hepatocytes and flows in bile canaliculi toward the periphery of the lobule where it enters branches of the bile duct. 100x
![Hepatocytes <p>The classic liver lobule is more clearly demarcated by connective tissue in a pig than in the human. Blood enters the liver in the hepatic portal vein or hepatic artery; branches of both vessels are located in a portal canal. From these branches, blood enters hepatic sinusoids between plates of hepatocytes and is carried into the central vein. Bile is produced by the hepatocytes and flows in bile canaliculi toward the periphery of the lobule where it enters branches of the bile duct. 100x</p>](https://digitalhistology.org/wp-content/uploads/2017/10/Or.Dig_.MajGl_.Liv-2-5-ping.png)
Hepatocytes
The classic liver lobule is more clearly demarcated by connective tissue in a pig than in the human. Blood enters the liver in the hepatic portal vein or hepatic artery; branches of both vessels are located in a portal canal. From these branches, blood enters hepatic sinusoids between plates of hepatocytes and is carried into the central vein. Bile is produced by the hepatocytes and flows in bile canaliculi toward the periphery of the lobule where it enters branches of the bile duct. 100x
![Connective tissue <p>The classic liver lobule is more clearly demarcated by connective tissue in a pig than in the human. Blood enters the liver in the hepatic portal vein or hepatic artery; branches of both vessels are located in a portal canal. From these branches, blood enters hepatic sinusoids between plates of hepatocytes and is carried into the central vein. Bile is produced by the hepatocytes and flows in bile canaliculi toward the periphery of the lobule where it enters branches of the bile duct. 100x</p>](https://digitalhistology.org/wp-content/uploads/2017/10/Or.Dig_.MajGl_.Liv-2-6-ping.png)
Connective tissue
The classic liver lobule is more clearly demarcated by connective tissue in a pig than in the human. Blood enters the liver in the hepatic portal vein or hepatic artery; branches of both vessels are located in a portal canal. From these branches, blood enters hepatic sinusoids between plates of hepatocytes and is carried into the central vein. Bile is produced by the hepatocytes and flows in bile canaliculi toward the periphery of the lobule where it enters branches of the bile duct. 100x
![Direction of blood flow <p>The classic liver lobule is more clearly demarcated by connective tissue in a pig than in the human. Blood enters the liver in the hepatic portal vein or hepatic artery; branches of both vessels are located in a portal canal. From these branches, blood enters hepatic sinusoids between plates of hepatocytes and is carried into the central vein. Bile is produced by the hepatocytes and flows in bile canaliculi toward the periphery of the lobule where it enters branches of the bile duct. 100x</p>](https://digitalhistology.org/wp-content/uploads/2017/10/Or.Dig_.MajGl_.Liv-2-7-ping.png)
Direction of blood flow
The classic liver lobule is more clearly demarcated by connective tissue in a pig than in the human. Blood enters the liver in the hepatic portal vein or hepatic artery; branches of both vessels are located in a portal canal. From these branches, blood enters hepatic sinusoids between plates of hepatocytes and is carried into the central vein. Bile is produced by the hepatocytes and flows in bile canaliculi toward the periphery of the lobule where it enters branches of the bile duct. 100x
![Direction of bile flow <p>The classic liver lobule is more clearly demarcated by connective tissue in a pig than in the human. Blood enters the liver in the hepatic portal vein or hepatic artery; branches of both vessels are located in a portal canal. From these branches, blood enters hepatic sinusoids between plates of hepatocytes and is carried into the central vein. Bile is produced by the hepatocytes and flows in bile canaliculi toward the periphery of the lobule where it enters branches of the bile duct. 100x</p>](https://digitalhistology.org/wp-content/uploads/2024/05/Or.Dig_.MajGl_.Liv-2-8-ping.png)
Direction of bile flow
The classic liver lobule is more clearly demarcated by connective tissue in a pig than in the human. Blood enters the liver in the hepatic portal vein or hepatic artery; branches of both vessels are located in a portal canal. From these branches, blood enters hepatic sinusoids between plates of hepatocytes and is carried into the central vein. Bile is produced by the hepatocytes and flows in bile canaliculi toward the periphery of the lobule where it enters branches of the bile duct. 100x