Metaphase

During metaphase, sister chromatids align at the metaphase plate (equatorial plate), midway between the poles. Formation of the mitotic spindle is completed.

During metaphase, sister chromatids align at the metaphase plate (equatorial plate), midway between the poles. Formation of the mitotic spindle is completed.

The centromere is a highly condensed region of DNA which forms the junction point for the two sister chromatids. A protein complex located on the centromere, the kinetochore, provides the attachment point for microtubules of the spindle apparatus.

Microtubules of the spindle apparatus extend from the diplosome of the centrosome and consists of three types. Kinetochore microtubules, attach to the kinetochore of the chromatids. Polar microtubules overlap with each in the center of the spindle, interacting with each other to push the spindle poles apart. Astral microtubules extend away from the spindle to provide anchorage for the spindle.

Microtubules of the spindle apparatus extend from the diplosome of the centrosome and consists of three types. Kinetochore microtubules, attach to the kinetochore of the chromatids. Polar microtubules overlap with each in the center of the spindle, interacting with each other to push the spindle poles apart. Astral microtubules extend away from the spindle to provide anchorage for the spindle.

Microtubules of the spindle apparatus extend from the diplosome of the centrosome and consists of three types. Kinetochore microtubules, attach to the kinetochore of the chromatids. Polar microtubules overlap with each in the center of the spindle, interacting with each other to push the spindle poles apart. Astral microtubules extend away from the spindle to provide anchorage for the spindle.

Microtubules of the spindle apparatus extend from the diplosome of the centrosome and consists of three types. Kinetochore microtubules, attach to the kinetochore of the chromatids. Polar microtubules overlap with each in the center of the spindle, interacting with each other to push the spindle poles apart. Astral microtubules extend away from the spindle to provide anchorage for the spindle.

Microtubules of the spindle apparatus extend from the diplosome of the centrosome and consists of three types. Kinetochore microtubules, attach to the kinetochore of the chromatids. Polar microtubules overlap with each in the center of the spindle, interacting with each other to push the spindle poles apart. Astral microtubules extend away from the spindle to provide anchorage for the spindle.