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Metaphase
During metaphase, sister chromatids align at the metaphase plate (equatorial plate), midway between the poles. Formation of the mitotic spindle is completed.
![Metaphase plate <p>During metaphase, sister chromatids align at the metaphase plate (equatorial plate), midway between the poles. Formation of the mitotic spindle is completed.</p>](https://digitalhistology.org/wp-content/uploads/2019/04/C.CD_.MIT-5-5-ping.png)
Metaphase plate
During metaphase, sister chromatids align at the metaphase plate (equatorial plate), midway between the poles. Formation of the mitotic spindle is completed.
![Sister chromatids <p>During metaphase, sister chromatids align at the metaphase plate (equatorial plate), midway between the poles. Formation of the mitotic spindle is completed.</p>](https://digitalhistology.org/wp-content/uploads/2017/05/C.CD_.MIT-5-1-ping.png)
Sister chromatids
During metaphase, sister chromatids align at the metaphase plate (equatorial plate), midway between the poles. Formation of the mitotic spindle is completed.
![Centromeres > <p>The centromere is a highly condensed region of DNA which forms the junction point for the two sister chromatids. A protein complex located on the centromere, the kinetochore, provides the attachment point for microtubules of the spindle apparatus.</p>](https://digitalhistology.org/wp-content/uploads/2017/05/C.CD_.MIT-5-2-ping.png)
Centromeres >
The centromere is a highly condensed region of DNA which forms the junction point for the two sister chromatids. A protein complex located on the centromere, the kinetochore, provides the attachment point for microtubules of the spindle apparatus.
![Mitotic spindle > <p>Microtubules of the spindle apparatus extend from the centrioles of the centrosome. One set attaches to the kinetochore of the chromatids (kinetochore microtubules); one set overlaps with opposing microtubules at the midline; and a third set extends away from the spindle (astral microtubles).</p>](https://digitalhistology.org/wp-content/uploads/2017/05/C.CD_.MIT-5-3-ping.png)
Mitotic spindle >
Microtubules of the spindle apparatus extend from the centrioles of the centrosome. One set attaches to the kinetochore of the chromatids (kinetochore microtubules); one set overlaps with opposing microtubules at the midline; and a third set extends away from the spindle (astral microtubles).
![Centrosomes <p>Microtubules of the spindle apparatus extend from the centrioles of the centrosome. One set attaches to the kinetochore of the chromatids (kinetochore microtubules); one set overlaps with opposing microtubules at the midline; and a third set extends away from the spindle (astral microtubles).</p>](https://digitalhistology.org/wp-content/uploads/2017/05/C.CD_.MIT-5-4-ping.png)
Centrosomes
Microtubules of the spindle apparatus extend from the centrioles of the centrosome. One set attaches to the kinetochore of the chromatids (kinetochore microtubules); one set overlaps with opposing microtubules at the midline; and a third set extends away from the spindle (astral microtubles).