Lymph node
This low magnification image of a lymph node shows the distinct histology of the cortex and medulla. The section also includes a large portion of the hilum. Due to the plane of section, a portion of the cortex appears disconnected, separated by a portion of the hilum. The node is surrounded by adipose tissue. 40x
Cortex >
The outer cortex (superficial cortex, nodular cortex) contains lymphoid nodules that are populated mostly by B lymphocytes. The inner paracortex (deep cortex) resembles diffuse lymphoid tissue and is populated mostly by T lymphocytes.
- Outer cortex
The outer cortex (superficial cortex, nodular cortex) contains lymphoid nodules that are populated mostly by B lymphocytes. The inner paracortex (deep cortex) resembles diffuse lymphoid tissue and is populated mostly by T lymphocytes.
- Deep cortex (paracortex)
The outer cortex (superficial cortex, nodular cortex) contains lymphoid nodules that are populated mostly by B lymphocytes. The inner paracortex (deep cortex) resembles diffuse lymphoid tissue and is populated mostly by T lymphocytes.
- Lymphoid nodules
The outer cortex (superficial cortex, nodular cortex) contains lymphoid nodules that are populated mostly by B lymphocytes. The inner paracortex (deep cortex) resembles diffuse lymphoid tissue and is populated mostly by T lymphocytes.
Medulla >
The medulla consists of a series of medullary cords (B-dependent areas), that are finger-like projections of lymphoid tissue. Between the cords are large channels, called medullary sinuses, that receive lymph from the cortical sinuses. The medullary sinuses contain large numbers of lymphocytes.
- Medullary cords
The medulla consists of a series of medullary cords (B-dependent areas), that are finger-like projections of lymphoid tissue. Between the cords are large channels, called medullary sinuses, that receive lymph from the cortical sinuses. The medullary sinuses contain large numbers of lymphocytes.
- Medullary sinuses
The medulla consists of a series of medullary cords (B-dependent areas), that are finger-like projections of lymphoid tissue. Between the cords are large channels, called medullary sinuses, that receive lymph from the cortical sinuses. The medullary sinuses contain large numbers of lymphocytes.
Hilum >
The hilum is the indented portion of lymph nodes where efferent lymphatics and venules exit and where arterioles enter. The hilum contains a network of anastomosing efferent vessels that receive lymph passing through the medullary sinuses. Filling the hilum is supporting connective tissue and adipose tissue.
Efferent lymphatics
The hilum is the indented portion of lymph nodes where the efferent lymphatics and venules exit and where arterioles enter. The hilum contains a network of anastomosing efferent vessels that receive the lymph passing through the medullary sinuses. Filling the hilum is supporting connective tissue and adipose tissue.
Blood vessels
The hilum is the indented portion of lymph nodes where the efferent lymphatics and venules exit and where arterioles enter. The hilum contains a network of anastomosing efferent vessels that receive the lymph passing through the medullary sinuses. Filling the hilum is supporting connective tissue and adipose tissue.
Image source >
Image taken of a slide from the University of Michigan collection.
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