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Receptors

Pacinian corpuscles are encapsulated sensory receptors located in connective tissue deep in the skin or just beneath the skin.  Pacinian corpuscles consist of a centrally located axon surrounded by multiple layers of endoneurial and Schwann cells.  These receptors respond to pressure and vibration and can be up to 1 mm in diameter.  400x

Pacinian corpuscle > <p>Pacinian corpuscles consist of concentric layers of endoneurial cells and Schwann cells, which surround a central, unmyelinated axon.  When cut in cross section, the internal structure of the receptor resembles a sliced onion, and the lymph-like fluid between the lamellae allows the receptor to adapt and respond to stimuli for deep pressure and vibration.</p>

Pacinian corpuscle >

Pacinian corpuscles consist of concentric layers of endoneurial cells and Schwann cells, which surround a central, unmyelinated axon.  When cut in cross section, the internal structure of the receptor resembles a sliced onion, and the lymph-like fluid between the lamellae allows the receptor to adapt and respond to stimuli for deep pressure and vibration.

Axon <p>Pacinian corpuscles consist of concentric layers of endoneurial cells and Schwann cells, which surround a central, unmyelinated axon.  When cut in cross section, the internal structure of the receptor resembles a sliced onion, and the lymph-like fluid between the lamellae allows the receptor to adapt and respond to stimuli for deep pressure and vibration.</p>

Axon

Pacinian corpuscles consist of concentric layers of endoneurial cells and Schwann cells, which surround a central, unmyelinated axon.  When cut in cross section, the internal structure of the receptor resembles a sliced onion, and the lymph-like fluid between the lamellae allows the receptor to adapt and respond to stimuli for deep pressure and vibration.

Endoneurial and Schwann cells <p>Pacinian corpuscles consist of concentric layers of endoneurial cells and Schwann cells, which surround a central, unmyelinated axon.  When cut in cross section, the internal structure of the receptor resembles a sliced onion, and the lymph-like fluid between the lamellae allows the receptor to adapt and respond to stimuli for deep pressure and vibration.</p>

Endoneurial and Schwann cells

Pacinian corpuscles consist of concentric layers of endoneurial cells and Schwann cells, which surround a central, unmyelinated axon.  When cut in cross section, the internal structure of the receptor resembles a sliced onion, and the lymph-like fluid between the lamellae allows the receptor to adapt and respond to stimuli for deep pressure and vibration.