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Receptors
Pacinian corpuscles are encapsulated sensory receptors located in connective tissues throughout the body, but are most numerous in the deep layers of the skin. Pacinian corpuscles consist of a centrally located axon surrounded by multiple layers of endoneurial and Schwann cells. These receptors respond to pressure and vibration and can be up to 1 mm in diameter. 400x
![Pacinian corpuscle > <p>Pacinian corpuscles consist of concentric layers of endoneurial cells and Schwann cells, which surround a central, unmyelinated axon. When cut in cross section, the internal structure of the receptor resembles a sliced onion, and the lymph-like fluid between the lamellae allows the receptor to adapt and respond to stimuli for deep pressure and vibration.</p>](https://digitalhistology.org/wp-content/uploads/2017/05/T.N.Rec-2-1-ping.png)
Pacinian corpuscle >
Pacinian corpuscles consist of concentric layers of endoneurial cells and Schwann cells, which surround a central, unmyelinated axon. When cut in cross section, the internal structure of the receptor resembles a sliced onion, and the lymph-like fluid between the lamellae allows the receptor to adapt and respond to stimuli for deep pressure and vibration.
![Axon <p>Pacinian corpuscles consist of concentric layers of endoneurial cells and Schwann cells, which surround a central, unmyelinated axon. When cut in cross section, the internal structure of the receptor resembles a sliced onion, and the lymph-like fluid between the lamellae allows the receptor to adapt and respond to stimuli for deep pressure and vibration.</p>](https://digitalhistology.org/wp-content/uploads/2017/05/T.N.Rec-1-2-ping-1.png)
Axon
Pacinian corpuscles consist of concentric layers of endoneurial cells and Schwann cells, which surround a central, unmyelinated axon. When cut in cross section, the internal structure of the receptor resembles a sliced onion, and the lymph-like fluid between the lamellae allows the receptor to adapt and respond to stimuli for deep pressure and vibration.
![Endoneurial and Schwann cells <p>Pacinian corpuscles consist of concentric layers of endoneurial cells and Schwann cells, which surround a central, unmyelinated axon. When cut in cross section, the internal structure of the receptor resembles a sliced onion, and the lymph-like fluid between the lamellae allows the receptor to adapt and respond to stimuli for deep pressure and vibration.</p>](https://digitalhistology.org/wp-content/uploads/2017/05/T.N.Rec-1-3-ping-1.png)
Endoneurial and Schwann cells
Pacinian corpuscles consist of concentric layers of endoneurial cells and Schwann cells, which surround a central, unmyelinated axon. When cut in cross section, the internal structure of the receptor resembles a sliced onion, and the lymph-like fluid between the lamellae allows the receptor to adapt and respond to stimuli for deep pressure and vibration.