Peripheral nerve
These longitudinal sections show fascicles of peripheral nerves at low (l) and high (r) magnifications. Each fascicle is immediately surrounded by a compact perineurium and epineurium. The epineurium between fascicles appears more loosely organized. The perineurium is distinctly more basophilic than the more collagenous, eosinophilic epineurium. Within the nerve, individual myelinated axons are surrounded by an endoneurium. 100x, 800x
Fascicles
These longitudinal sections show fascicles of peripheral nerves at low (l) and high (r) magnifications. Each fascicle is immediately surrounded by a compact perineurium and epineurium. The epineurium between fascicles appears more loosely organized. The perineurium is distinctly more basophilic than the more collagenous, eosinophilic epineurium. Within the nerve, individual myelinated axons are surrounded by an endoneurium. 100x, 800x
Epineurium >
The epineurium consists of dense irregular connective tissue that surrounds the nerve and contains adipocytes as well as blood vessels. The perineurium, produced by perineurial cells, is a specialized, metabolically active connective tissue that contributes to the blood-nerve-barrier. The endoneurium is a product of both fibroblasts and Schwann cells and surrounds individual myelinated axons as well as Schwann cells ensheathing unmyelinated axons.
Perineurium
The epineurium consists of dense irregular connective tissue that surrounds the nerve and contains adipocytes as well as blood vessels. The perineurium, produced by perineurial cells, is a specialized, metabolically active connective tissue that contributes to the blood-nerve-barrier. The endoneurium is a product of both fibroblasts and Schwann cells and surrounds individual myelinated axons as well as Schwann cells ensheathing unmyelinated axons.
Endoneurium
The epineurium consists of dense irregular connective tissue that surrounds the nerve and contains adipocytes as well as blood vessels. The perineurium, produced by perineurial cells, is a specialized, metabolically active connective tissue that contributes to the blood-nerve-barrier. The endoneurium is a product of both fibroblasts and Schwann cells and surrounds individual myelinated axons as well as Schwann cells ensheathing unmyelinated axons.
Axons
These longitudinal sections show fascicles of peripheral nerves at low (l) and high (r) magnifications. Each fascicle is immediately surrounded by a compact perineurium and epineurium. The epineurium between fascicles appears more loosely organized. The perineurium is distinctly more basophilic than the more collagenous, eosinophilic epineurium. Within the nerve, individual myelinated axons are surrounded by an endoneurium. 100x, 800x
Myelin sheaths
These longitudinal sections show fascicles of peripheral nerves at low (l) and high (r) magnifications. Each fascicle is immediately surrounded by a compact perineurium and epineurium. The epineurium between fascicles appears more loosely organized. The perineurium is distinctly more basophilic than the more collagenous, eosinophilic epineurium. Within the nerve, individual myelinated axons are surrounded by an endoneurium. 100x, 800x
Schwann cell nuclei
These longitudinal sections show fascicles of peripheral nerves at low (l) and high (r) magnifications. Each fascicle is immediately surrounded by a compact perineurium and epineurium. The epineurium between fascicles appears more loosely organized. The perineurium is distinctly more basophilic than the more collagenous, eosinophilic epineurium. Within the nerve, individual myelinated axons are surrounded by an endoneurium. 100x, 800x