Digital Histology
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Hemidesmosomes

Hemidesmosomes are prominent in the basal layer of the epidermis.  Structurally, they consist of one-half of a desmosome and serve to anchor an epithelium to its underlying basal lamina.  The associated keratin intermediate filaments insert into the attachment plaques.  Transmembrane proteins extend from the plaque into the basal lamina to provide attachment.  30,000x

Epidermal cell <p>Hemidesmosomes are prominent in the basal layer of the epidermis.  Structurally, they consist of one-half of a desmosome and serve to anchor an epithelium to its underlying basal lamina.  The associated keratin intermediate filaments insert into the attachment plaques.  Transmembrane proteins extend from the plaque into the basal lamina to provide attachment.  30,000x</p>

Epidermal cell

Hemidesmosomes are prominent in the basal layer of the epidermis.  Structurally, they consist of one-half of a desmosome and serve to anchor an epithelium to its underlying basal lamina.  The associated keratin intermediate filaments insert into the attachment plaques.  Transmembrane proteins extend from the plaque into the basal lamina to provide attachment.  30,000x
Connective tissue <p>Hemidesmosomes are prominent in the basal layer of the epidermis.  Structurally, they consist of one-half of a desmosome and serve to anchor an epithelium to its underlying basal lamina.  The associated keratin intermediate filaments insert into the attachment plaques.  Transmembrane proteins extend from the plaque into the basal lamina to provide attachment.  30,000x</p>

Connective tissue

Hemidesmosomes are prominent in the basal layer of the epidermis.  Structurally, they consist of one-half of a desmosome and serve to anchor an epithelium to its underlying basal lamina.  The associated keratin intermediate filaments insert into the attachment plaques.  Transmembrane proteins extend from the plaque into the basal lamina to provide attachment.  30,000x
Hemidesmosomes <p>Hemidesmosomes are prominent in the basal layer of the epidermis.  Structurally, they consist of one-half of a desmosome and serve to anchor an epithelium to its underlying basal lamina.  The associated keratin intermediate filaments insert into the attachment plaques.  Transmembrane proteins extend from the plaque into the basal lamina to provide attachment.  30,000x</p>

Hemidesmosomes

Hemidesmosomes are prominent in the basal layer of the epidermis.  Structurally, they consist of one-half of a desmosome and serve to anchor an epithelium to its underlying basal lamina.  The associated keratin intermediate filaments insert into the attachment plaques.  Transmembrane proteins extend from the plaque into the basal lamina to provide attachment.  30,000x
- Attachment plaques <p>Hemidesmosomes are prominent in the basal layer of the epidermis.  Structurally, they consist of one-half of a desmosome and serve to anchor an epithelium to its underlying basal lamina.  The associated keratin intermediate filaments insert into the attachment plaques.  Transmembrane proteins extend from the plaque into the basal lamina to provide attachment.  30,000x</p>

- Attachment plaques

Hemidesmosomes are prominent in the basal layer of the epidermis.  Structurally, they consist of one-half of a desmosome and serve to anchor an epithelium to its underlying basal lamina.  The associated keratin intermediate filaments insert into the attachment plaques.  Transmembrane proteins extend from the plaque into the basal lamina to provide attachment.  30,000x
- Keratin filaments <p>Hemidesmosomes are prominent in the basal layer of the epidermis.  Structurally, they consist of one-half of a desmosome and serve to anchor an epithelium to its underlying basal lamina.  The associated keratin intermediate filaments insert into the attachment plaques.  Transmembrane proteins extend from the plaque into the basal lamina to provide attachment.  30,000x</p>

- Keratin filaments

Hemidesmosomes are prominent in the basal layer of the epidermis.  Structurally, they consist of one-half of a desmosome and serve to anchor an epithelium to its underlying basal lamina.  The associated keratin intermediate filaments insert into the attachment plaques.  Transmembrane proteins extend from the plaque into the basal lamina to provide attachment.  30,000x
Plasma membrane <p>Hemidesmosomes are prominent in the basal layer of the epidermis.  Structurally, they consist of one-half of a desmosome and serve to anchor an epithelium to its underlying basal lamina.  The associated keratin intermediate filaments insert into the attachment plaques.  Transmembrane proteins extend from the plaque into the basal lamina to provide attachment.  30,000x</p>

Plasma membrane

Hemidesmosomes are prominent in the basal layer of the epidermis.  Structurally, they consist of one-half of a desmosome and serve to anchor an epithelium to its underlying basal lamina.  The associated keratin intermediate filaments insert into the attachment plaques.  Transmembrane proteins extend from the plaque into the basal lamina to provide attachment.  30,000x
Lamina densa of basal lamina <p>Hemidesmosomes are prominent in the basal layer of the epidermis.  Structurally, they consist of one-half of a desmosome and serve to anchor an epithelium to its underlying basal lamina.  The associated keratin intermediate filaments insert into the attachment plaques.  Transmembrane proteins extend from the plaque into the basal lamina to provide attachment.  30,000x</p>

Lamina densa of basal lamina

Hemidesmosomes are prominent in the basal layer of the epidermis.  Structurally, they consist of one-half of a desmosome and serve to anchor an epithelium to its underlying basal lamina.  The associated keratin intermediate filaments insert into the attachment plaques.  Transmembrane proteins extend from the plaque into the basal lamina to provide attachment.  30,000x
Main SlideEpidermal cellConnective tissueHemidesmosomes - Attachment plaques - Keratin filamentsPlasma membraneLamina densa of basal lamina