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Macrophage

Macrophages are the major phagocytic cell in connective tissue. They are derived from blood-borne monocytes (upper left) that migrate into the tissue (two lower left panels). The ultrastructure of a macrophage is shown on the right. Macrophage nuclei are oval-shaped and frequently indented, reflecting the cell’s origin from a monocyte. The pink cytoplasm, when visible, contains numerous lysosomes and phagocytosed material. 1000x (LM), 8000x (EM)

Monocyte in blood <p>Macrophages are the major phagocytic cell in connective tissue. They are derived from blood-borne monocytes (upper left) that migrate into the tissue (two lower left panels). The ultrastructure of a macrophage is shown on the right. Macrophage nuclei are oval-shaped and frequently indented, reflecting the cell’s origin from a monocyte. The pink cytoplasm, when visible, contains numerous lysosomes and phagocytosed material. 1000x (LM), 8000x (EM)</p>

Monocyte in blood

Macrophages are the major phagocytic cell in connective tissue. They are derived from blood-borne monocytes (upper left) that migrate into the tissue (two lower left panels). The ultrastructure of a macrophage is shown on the right. Macrophage nuclei are oval-shaped and frequently indented, reflecting the cell’s origin from a monocyte. The pink cytoplasm, when visible, contains numerous lysosomes and phagocytosed material. 1000x (LM), 8000x (EM)

Macrophages in tissue <p>Macrophages are the major phagocytic cell in connective tissue. They are derived from blood-borne monocytes (upper left) that migrate into the tissue (two lower left panels). The ultrastructure of a macrophage is shown on the right. Macrophage nuclei are oval-shaped and frequently indented, reflecting the cell’s origin from a monocyte. The pink cytoplasm, when visible, contains numerous lysosomes and phagocytosed material. 1000x (LM), 8000x (EM)</p>

Macrophages in tissue

Macrophages are the major phagocytic cell in connective tissue. They are derived from blood-borne monocytes (upper left) that migrate into the tissue (two lower left panels). The ultrastructure of a macrophage is shown on the right. Macrophage nuclei are oval-shaped and frequently indented, reflecting the cell’s origin from a monocyte. The pink cytoplasm, when visible, contains numerous lysosomes and phagocytosed material. 1000x (LM), 8000x (EM)

Nuclear indentation <p>Macrophages are the major phagocytic cell in connective tissue. They are derived from blood-borne monocytes (upper left) that migrate into the tissue (two lower left panels). The ultrastructure of a macrophage is shown on the right. Macrophage nuclei are oval-shaped and frequently indented, reflecting the cell’s origin from a monocyte. The pink cytoplasm, when visible, contains numerous lysosomes and phagocytosed material. 1000x (LM), 8000x (EM)</p>

Nuclear indentation

Macrophages are the major phagocytic cell in connective tissue. They are derived from blood-borne monocytes (upper left) that migrate into the tissue (two lower left panels). The ultrastructure of a macrophage is shown on the right. Macrophage nuclei are oval-shaped and frequently indented, reflecting the cell’s origin from a monocyte. The pink cytoplasm, when visible, contains numerous lysosomes and phagocytosed material. 1000x (LM), 8000x (EM)

Cytoplasm <p>Macrophages are the major phagocytic cell in connective tissue. They are derived from blood-borne monocytes (upper left) that migrate into the tissue (two lower left panels). The ultrastructure of a macrophage is shown on the right. Macrophage nuclei are oval-shaped and frequently indented, reflecting the cell’s origin from a monocyte. The pink cytoplasm, when visible, contains numerous lysosomes and phagocytosed material. 1000x (LM), 8000x (EM)</p>

Cytoplasm

Macrophages are the major phagocytic cell in connective tissue. They are derived from blood-borne monocytes (upper left) that migrate into the tissue (two lower left panels). The ultrastructure of a macrophage is shown on the right. Macrophage nuclei are oval-shaped and frequently indented, reflecting the cell’s origin from a monocyte. The pink cytoplasm, when visible, contains numerous lysosomes and phagocytosed material. 1000x (LM), 8000x (EM)

Lysosomes <p>Macrophages are the major phagocytic cell in connective tissue. They are derived from blood-borne monocytes (upper left) that migrate into the tissue (two lower left panels). The ultrastructure of a macrophage is shown on the right. Macrophage nuclei are oval-shaped and frequently indented, reflecting the cell’s origin from a monocyte. The pink cytoplasm, when visible, contains numerous lysosomes and phagocytosed material. 1000x (LM), 8000x (EM)</p>

Lysosomes

Macrophages are the major phagocytic cell in connective tissue. They are derived from blood-borne monocytes (upper left) that migrate into the tissue (two lower left panels). The ultrastructure of a macrophage is shown on the right. Macrophage nuclei are oval-shaped and frequently indented, reflecting the cell’s origin from a monocyte. The pink cytoplasm, when visible, contains numerous lysosomes and phagocytosed material. 1000x (LM), 8000x (EM)

Membrane ruffles > <p>Macrophages are highly motile, phagocytic cells and possess a heavily folded and ruffled plasma membrane.</p>

Membrane ruffles >

Macrophages are highly motile, phagocytic cells and possess a heavily folded and ruffled plasma membrane.

Main Slide Monocyte in blood Macrophages in tissue Nuclear indentation Cytoplasm Lysosomes Membrane ruffles >