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Bone: endochondral ossification
The chondrocytes in this future primary center of ossification have begun to mature and hypertrophy. The matrix surrounding these cells has not yet calcified. Hyaline cartilage cells on either side of this central region show progressive changes toward maturation. 200x
![Maturation and hypertrophy <p>The chondrocytes in this future primary center of ossification have begun to mature and hypertrophy. The matrix surrounding these cells has not yet calcified. Hyaline cartilage cells on either side of this central region show progressive changes toward maturation. 200x</p>](https://digitalhistology.org/wp-content/uploads/2018/02/T.C.B.F.E.02.P01.png)
Maturation and hypertrophy
The chondrocytes in this future primary center of ossification have begun to mature and hypertrophy. The matrix surrounding these cells has not yet calcified. Hyaline cartilage cells on either side of this central region show progressive changes toward maturation. 200x
![Beginning maturation <p>The chondrocytes in this future primary center of ossification have begun to mature and hypertrophy. The matrix surrounding these cells has not yet calcified. Hyaline cartilage cells on either side of this central region show progressive changes toward maturation. 200x</p>](https://digitalhistology.org/wp-content/uploads/2018/02/T.C.B.F.E.02.P02.png)
Beginning maturation
The chondrocytes in this future primary center of ossification have begun to mature and hypertrophy. The matrix surrounding these cells has not yet calcified. Hyaline cartilage cells on either side of this central region show progressive changes toward maturation. 200x
![Normal cartilage <p>The chondrocytes in this future primary center of ossification have begun to mature and hypertrophy. The matrix surrounding these cells has not yet calcified. Hyaline cartilage cells on either side of this central region show progressive changes toward maturation. 200x</p>](https://digitalhistology.org/wp-content/uploads/2018/02/T.C.B.F.E.02.P03.png)
Normal cartilage
The chondrocytes in this future primary center of ossification have begun to mature and hypertrophy. The matrix surrounding these cells has not yet calcified. Hyaline cartilage cells on either side of this central region show progressive changes toward maturation. 200x
![Perichondrium <p>The chondrocytes in this future primary center of ossification have begun to mature and hypertrophy. The matrix surrounding these cells has not yet calcified. Hyaline cartilage cells on either side of this central region show progressive changes toward maturation. 200x</p>](https://digitalhistology.org/wp-content/uploads/2018/02/T.C.B.F.E.02.P04.png)
Perichondrium
The chondrocytes in this future primary center of ossification have begun to mature and hypertrophy. The matrix surrounding these cells has not yet calcified. Hyaline cartilage cells on either side of this central region show progressive changes toward maturation. 200x