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Stratum basale
These images compare the light and electron microscopic appearance of cells in the stratum basale. The large bundles of keratin filaments (tonofilaments) are clearly visible at the light and electron microscopic level. The keratin filaments insert into desmosomes on the lateral and apical surfaces of the cell. They also insert into hemidesmosomes along the basal surface, adjacent to the basal lamina. 1000x, 4000x

Stratum basale
These images compare the light and electron microscopic appearance of cells in the stratum basale. The large bundles of keratin filaments (tonofilaments) are clearly visible at the light and electron microscopic level. The keratin filaments insert into desmosomes on the lateral and apical surfaces of the cell. They also insert into hemidesmosomes along the basal surface, adjacent to the basal lamina. 1000x, 4000x

- Tonofilaments
These images compare the light and electron microscopic appearance of cells in the stratum basale. The large bundles of keratin filaments (tonofilaments) are clearly visible at the light and electron microscopic level. The keratin filaments insert into desmosomes on the lateral and apical surfaces of the cell. They also insert into hemidesmosomes along the basal surface, adjacent to the basal lamina. 1000x, 4000x

- Melanosomes
These images compare the light and electron microscopic appearance of cells in the stratum basale. The large bundles of keratin filaments (tonofilaments) are clearly visible at the light and electron microscopic level. The keratin filaments insert into desmosomes on the lateral and apical surfaces of the cell. They also insert into hemidesmosomes along the basal surface, adjacent to the basal lamina. 1000x, 4000x

Stratum spinosum
These images compare the light and electron microscopic appearance of cells in the stratum basale. The large bundles of keratin filaments (tonofilaments) are clearly visible at the light and electron microscopic level. The keratin filaments insert into desmosomes on the lateral and apical surfaces of the cell. They also insert into hemidesmosomes along the basal surface, adjacent to the basal lamina. 1000x, 4000x

Dermis (papillary layer)
These images compare the light and electron microscopic appearance of cells in the stratum basale. The large bundles of keratin filaments (tonofilaments) are clearly visible at the light and electron microscopic level. The keratin filaments insert into desmosomes on the lateral and apical surfaces of the cell. They also insert into hemidesmosomes along the basal surface, adjacent to the basal lamina. 1000x, 4000x