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Stratum corneum - Thin skin
There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x
![Epidermis <p>There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x</p>](https://digitalhistology.org/wp-content/uploads/2023/12/Or.Sk_.Epi-19-1-ping-Epi.png)
Epidermis
There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x
![Stratum basale <p>There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x</p>](https://digitalhistology.org/wp-content/uploads/2023/12/Or.Sk_.Epi-19-2-ping-sb.png)
Stratum basale
There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x
![Stratum spinosum <p>There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x</p>](https://digitalhistology.org/wp-content/uploads/2023/12/Or.Sk_.Epi-19-3-ping-SS.png)
Stratum spinosum
There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x
![Stratum granulosum <p>There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x</p>](https://digitalhistology.org/wp-content/uploads/2023/12/Or.Sk_.Epi-19-4-ping-SG.png)
Stratum granulosum
There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x
![Stratum corneum <p>There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x</p>](https://digitalhistology.org/wp-content/uploads/2023/12/Or.Sk_.Epi-19-5-ping-SC.png)
Stratum corneum
There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x
![- Squames <p>There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x</p>](https://digitalhistology.org/wp-content/uploads/2023/12/Or.Sk_.Epi-19-7-ping-sq.png)
- Squames
There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x
![Dermis <p>There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x</p>](https://digitalhistology.org/wp-content/uploads/2023/12/Or.Sk_.Epi-19-6-ping-DER.png)
Dermis
There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x
![Image source > <p>Image taken of a slide in the University of Iowa slide collection.</p>](https://digitalhistology.org/wp-content/uploads/2023/12/Iowa-source-ping-1.png)
Image source >
Image taken of a slide in the University of Iowa slide collection.