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Placenta: 1st trimester
All chorionic villi extend into the intervillous space filled with maternal blood. Each villus, with a central core of embryonic connective tissue and embryonic blood vessels, is covered by an inner layer of cytotrophoblastic cells and an outer layer of syncytiotrophoblast. 400x

Intervillous space
All chorionic villi extend into the intervillous space filled with maternal blood. Each villus, with a central core of embryonic connective tissue and embryonic blood vessels, is covered by an inner layer of cytotrophoblastic cells and an outer layer of syncytiotrophoblast. 400x

- Maternal blood
All chorionic villi extend into the intervillous space filled with maternal blood. Each villus, with a central core of embryonic connective tissue and embryonic blood vessels, is covered by an inner layer of cytotrophoblastic cells and an outer layer of syncytiotrophoblast. 400x

Floating villi
All chorionic villi extend into the intervillous space filled with maternal blood. Each villus, with a central core of embryonic connective tissue and embryonic blood vessels, is covered by an inner layer of cytotrophoblastic cells and an outer layer of syncytiotrophoblast. 400x

- Embryonic connective tissue
All chorionic villi extend into the intervillous space filled with maternal blood. Each villus, with a central core of embryonic connective tissue and embryonic blood vessels, is covered by an inner layer of cytotrophoblastic cells and an outer layer of syncytiotrophoblast. 400x

- Embryonic blood vessels
All chorionic villi extend into the intervillous space filled with maternal blood. Each villus, with a central core of embryonic connective tissue and embryonic blood vessels, is covered by an inner layer of cytotrophoblastic cells and an outer layer of syncytiotrophoblast. 400x

- Cytotrophoblast >
In the early placenta, cytotrophoblastic cells form a continuous, single-cell layer surrounding the embryonic connective tissue. These cells give rise to the multinucleated syncytiotrophoblast that lines the intervillous space.

- Syncytiotrophoblast
In the early placenta, cytotrophoblastic cells form a continuous, single-cell layer surrounding the embryonic connective tissue. These cells give rise to the multinucleated syncytiotrophoblast that lines the intervillous space.