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Ovary: secondary follicles

A secondary follicle forms as antral fluid accumulates in spaces among the proliferating follicle (granulosal) cells. The multiple antral spaces coalesce into a single, fluid-filled antrum. Granulosal cells surrounding the antrum are now called the stratum granulosum. The (non-human) follicle on the left is an earlier secondary follicle than the one on the right. 100x, 200x

Primary oocyte <p>A secondary follicle forms as antral fluid accumulates in spaces among the proliferating follicle (granulosal) cells. The multiple antral spaces coalesce into a single, fluid-filled antrum. Granulosal cells surrounding the antrum are now called the stratum granulosum. The (non-human) follicle on the left is an earlier secondary follicle than the one on the right. 100x, 200x </p>

Primary oocyte

A secondary follicle forms as antral fluid accumulates in spaces among the proliferating follicle (granulosal) cells. The multiple antral spaces coalesce into a single, fluid-filled antrum. Granulosal cells surrounding the antrum are now called the stratum granulosum. The (non-human) follicle on the left is an earlier secondary follicle than the one on the right. 100x, 200x

Zona pellucida <p>A secondary follicle forms as antral fluid accumulates in spaces among the proliferating follicle (granulosal) cells. The multiple antral spaces coalesce into a single, fluid-filled antrum. Granulosal cells surrounding the antrum are now called the stratum granulosum. The (non-human) follicle on the left is an earlier secondary follicle than the one on the right. 100x, 200x </p>

Zona pellucida

A secondary follicle forms as antral fluid accumulates in spaces among the proliferating follicle (granulosal) cells. The multiple antral spaces coalesce into a single, fluid-filled antrum. Granulosal cells surrounding the antrum are now called the stratum granulosum. The (non-human) follicle on the left is an earlier secondary follicle than the one on the right. 100x, 200x

Stratum granulosum <p>A secondary follicle forms as antral fluid accumulates in spaces among the proliferating follicle (granulosal) cells. The multiple antral spaces coalesce into a single, fluid-filled antrum. Granulosal cells surrounding the antrum are now called the stratum granulosum. The (non-human) follicle on the left is an earlier secondary follicle than the one on the right. 100x, 200x </p>

Stratum granulosum

A secondary follicle forms as antral fluid accumulates in spaces among the proliferating follicle (granulosal) cells. The multiple antral spaces coalesce into a single, fluid-filled antrum. Granulosal cells surrounding the antrum are now called the stratum granulosum. The (non-human) follicle on the left is an earlier secondary follicle than the one on the right. 100x, 200x

Antral spaces <p>A secondary follicle forms as antral fluid accumulates in spaces among the proliferating follicle (granulosal) cells. The multiple antral spaces coalesce into a single, fluid-filled antrum. Granulosal cells surrounding the antrum are now called the stratum granulosum. The (non-human) follicle on the left is an earlier secondary follicle than the one on the right. 100x, 200x </p>

Antral spaces

A secondary follicle forms as antral fluid accumulates in spaces among the proliferating follicle (granulosal) cells. The multiple antral spaces coalesce into a single, fluid-filled antrum. Granulosal cells surrounding the antrum are now called the stratum granulosum. The (non-human) follicle on the left is an earlier secondary follicle than the one on the right. 100x, 200x

Basement membrane <p>A secondary follicle forms as antral fluid accumulates in spaces among the proliferating follicle (granulosal) cells. The multiple antral spaces coalesce into a single, fluid-filled antrum. Granulosal cells surrounding the antrum are now called the stratum granulosum. The (non-human) follicle on the left is an earlier secondary follicle than the one on the right. 100x, 200x </p>

Basement membrane

A secondary follicle forms as antral fluid accumulates in spaces among the proliferating follicle (granulosal) cells. The multiple antral spaces coalesce into a single, fluid-filled antrum. Granulosal cells surrounding the antrum are now called the stratum granulosum. The (non-human) follicle on the left is an earlier secondary follicle than the one on the right. 100x, 200x

Theca interna > <p>The theca differentiates into a double layer surrounding the follicle. The theca interna is a highly vascularized layer of steroid-secreting cells located immediately external to the basement membrane; this layer synthesizes and secretes androgens in response to LH stimulation. Theca externa surrounds the interna and serves as a reserve-cell source for the interna.</p>

Theca interna >

The theca differentiates into a double layer surrounding the follicle. The theca interna is a highly vascularized layer of steroid-secreting cells located immediately external to the basement membrane; this layer synthesizes and secretes androgens in response to LH stimulation. Theca externa surrounds the interna and serves as a reserve-cell source for the interna.
Theca externa <p>The theca differentiates into a double layer surrounding the follicle. The theca interna is a highly vascularized layer of steroid-secreting cells located immediately external to the basement membrane; this layer synthesizes and secretes androgens in response to LH stimulation. Theca externa surrounds the interna and serves as a reserve-cell source for the interna.</p>

Theca externa

The theca differentiates into a double layer surrounding the follicle. The theca interna is a highly vascularized layer of steroid-secreting cells located immediately external to the basement membrane; this layer synthesizes and secretes androgens in response to LH stimulation. Theca externa surrounds the interna and serves as a reserve-cell source for the interna.
Main SlidePrimary oocyteZona pellucidaStratum granulosumAntral spacesBasement membraneTheca interna >Theca externa