Primary lymphoid nodule
Primary lymphoid nodules consist primarily of unstimulated lymphocytes that accumulate in tightly packed, spherical clusters in lymphoid tissues and organs. Lymphoid nodules filter the fluid in the layer or organ in which they are located; i.e., tissue fluid in the lamina propria, lymph in lymph node and blood in spleen. Antigens present in these filtrates initiate an immune response in these nodules. Colon, 200x; Fundic stomach, 100x
Primary lymphoid nodules >
Primary lymphoid nodules consists of a spherical mass of unstimulated lymphocytes. These primary nodules, located in the lamina propria of the colon (l) and stomach (r), filter tissue fluid and respond to antigens encountered by the mucosa. Following antigen stimulation, they can become a secondary nodule with the formation of a pale staining central region called the germinal center.
Diffuse lymphoid tissue
Primary lymphoid nodules consists of a spherical mass of unstimulated lymphocytes. These primary nodules, located in the lamina propria of the colon (l) and stomach (r), filter tissue fluid and respond to antigens encountered by the mucosa. Following antigen stimulation, they can become a secondary nodule with the formation of a pale staining central region called the germinal center.
Glands
Primary lymphoid nodules consists of a spherical mass of unstimulated lymphocytes. These primary nodules, located in the lamina propria of the colon (l) and stomach (r), filter tissue fluid and respond to antigens encountered by the mucosa. Following antigen stimulation, they can become a secondary nodule with the formation of a pale staining central region called the germinal center.
Muscularis mucosae
Primary lymphoid nodules consists of a spherical mass of unstimulated lymphocytes. These primary nodules, located in the lamina propria of the colon (l) and stomach (r), filter tissue fluid and respond to antigens encountered by the mucosa. Following antigen stimulation, they can become a secondary nodule with the formation of a pale staining central region called the germinal center.
Image sources >
These images were taken of slides from the University of Virginia (l) and the University of New England College of Osteopathic Medicine (r) collections.
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