Digital Histology
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Overview: Outer defense - Epithelium

Epithelium, such as epidermis of skin or mucosal epithelium lining digestive (shown above), respiratory, urinary or reproductive systems, serves as a barrier to microbes. After penetrating the epithelium (indicated by the long vertical arrow in the right panel), microbes enter a connective tissue layer, such as the dermis of skin or lamina propria of a mucosa, where they can elicit an inflammatory response or an immune response from neutrophils and mast cells. 1000x

Microbes <p>Epithelium, such as epidermis of skin or mucosae lining digestive, respiratory, urinary or reproductive systems, serves as a barrier to microbes. Microbes can penetrate these epithelia (indicated by the long vertical arrow in the right panel), and enter a connective tissue layer, such as the dermis of skin or lamina propria of a mucosa. Here, these cells can elicit an inflammatory response or an immune response from neutrophils and mast cells. 1000x</p>

Microbes

Epithelium, such as epidermis of skin or mucosae lining digestive, respiratory, urinary or reproductive systems, serves as a barrier to microbes. Microbes can penetrate these epithelia (indicated by the long vertical arrow in the right panel), and enter a connective tissue layer, such as the dermis of skin or lamina propria of a mucosa. Here, these cells can elicit an inflammatory response or an immune response from neutrophils and mast cells. 1000x
Epithelial barrier > <p>The epithelium (yellow arrows) provides a physical barrier to microbes, but also contains wandering immune cells (green arrows) like the macrophages seen here. These cells can provide local protection through phagocytosis and may also exit the epithelium to initiate an immune response elsewhere.</p>

Epithelial barrier >

The epithelium (yellow arrows) provides a physical barrier to microbes, but also contains wandering immune cells (green arrows) like the macrophages seen here. These cells can provide local protection through phagocytosis and may also exit the epithelium to initiate an immune response elsewhere.
Lamina propria > <p>The lamina propria contains additional phagocytic and immune-competent cells.</p>

Lamina propria >

The lamina propria contains additional phagocytic and immune-competent cells.
Main SlideMicrobesEpithelial barrier >Lamina propria >