Overview: Lymphoid nodules
These images show lymphoid nodules in MALT. Nodules result from initial antigen detection in diffuse lymphoid tissues and the subsequent recruitment of additional immune cells to the region. 200x, 400x, 400x
Primary nodules >
Primary nodules consist of spherical clusters of tightly-packed lymphocytes.
Secondary nodule >
Primary nodules progress to secondary nodules with the rapid proliferation of B cells in the center of the nodule. This response generates a pale-staining central region called the germinal center. Most nodules seen in MALT are secondary.
- Germinal center
Primary nodules progress to secondary nodules with the rapid proliferation of B cells in the center of the nodule. This response generates a pale-staining central region called the germinal center. Most nodules seen in MALT are secondary.
Image source >
This image was taken of a slide in the University of Mississippi slide collection.
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