Spleen: white pulp
As germinal centers enlarge within in the PALS, they displace the central arteriole to a more eccentric position, as seen here. Surrounding the lymphoid nodule is red pulp in which the splenic sinuses are completely filled with blood, obscuring the lumens. The junction of the white pulp with red pulp is referred to as the marginal zone, and sinuses located in this region are termed marginal sinuses. 200x
Lymphoid nodule
As germinal centers enlarge within in the PALS, they displace the central arteriole to a more eccentric position, as seen here. Surrounding the lymphoid nodule is red pulp in which the splenic sinuses are completely filled with blood, obscuring the lumens. The junction of the white pulp with red pulp is referred to as the marginal zone, and sinuses located in this region are termed marginal sinuses. 200x
Germinal center
As germinal centers enlarge within in the PALS, they displace the central arteriole to a more eccentric position, as seen here. Surrounding the lymphoid nodule is red pulp in which the splenic sinuses are completely filled with blood, obscuring the lumens. The junction of the white pulp with red pulp is referred to as the marginal zone, and sinuses located in this region are termed marginal sinuses. 200x
Periarterial lymphoid sheath (PALS)
As germinal centers enlarge within in the PALS, they displace the central arteriole to a more eccentric position, as seen here. Surrounding the lymphoid nodule is red pulp in which the splenic sinuses are completely filled with blood, obscuring the lumens. The junction of the white pulp with red pulp is referred to as the marginal zone, and sinuses located in this region are termed marginal sinuses. 200x
Central arteriole
As germinal centers enlarge within in the PALS, they displace the central arteriole to a more eccentric position, as seen here. Surrounding the lymphoid nodule is red pulp in which the splenic sinuses are completely filled with blood, obscuring the lumens. The junction of the white pulp with red pulp is referred to as the marginal zone, and sinuses located in this region are termed marginal sinuses. 200x
Marginal zone
As germinal centers enlarge within in the PALS, they displace the central arteriole to a more eccentric position, as seen here. Surrounding the lymphoid nodule is red pulp in which the splenic sinuses are completely filled with blood, obscuring the lumens. The junction of the white pulp with red pulp is referred to as the marginal zone, and sinuses located in this region are termed marginal sinuses. 200x
Red pulp
As germinal centers enlarge within in the PALS, they displace the central arteriole to a more eccentric position, as seen here. Surrounding the lymphoid nodule is red pulp in which the splenic sinuses are completely filled with blood, obscuring the lumens. The junction of the white pulp with red pulp is referred to as the marginal zone, and sinuses located in this region are termed marginal sinuses. 200x
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