![This is blank.](https://digitalhistology.org/wp-content/themes/histology-unified/imgs/trans.png)
Recto-anal junction
The epithelium changes abruptly at the junction of the rectum (simple columnar) with the anal canal (stratified squamous moist). The rectum resembles the rest of the large intestine, having straight intestinal glands with many goblet cells. A more gradual transition of the epithelium occurs between the anal canal and the anus, the latter being lined by a stratified squamous, keratinized epithelium. 100x
![Rectum <p>The epithelium changes abruptly at the junction of the rectum (simple columnar) with the anal canal (stratified squamous moist). The rectum resembles the rest of the large intestine, having straight intestinal glands with many goblet cells. A more gradual transition of the epithelium occurs between the anal canal and the anus, the latter being lined by a stratified squamous, keratinized epithelium. 100x</p>](https://digitalhistology.org/wp-content/uploads/2017/10/Or.Dig_.Tub_.LgI-11-1-ping.png)
Rectum
The epithelium changes abruptly at the junction of the rectum (simple columnar) with the anal canal (stratified squamous moist). The rectum resembles the rest of the large intestine, having straight intestinal glands with many goblet cells. A more gradual transition of the epithelium occurs between the anal canal and the anus, the latter being lined by a stratified squamous, keratinized epithelium. 100x
![Anal canal <p>The epithelium changes abruptly at the junction of the rectum (simple columnar) with the anal canal (stratified squamous moist). The rectum resembles the rest of the large intestine, having straight intestinal glands with many goblet cells. A more gradual transition of the epithelium occurs between the anal canal and the anus, the latter being lined by a stratified squamous, keratinized epithelium. 100x</p>](https://digitalhistology.org/wp-content/uploads/2017/10/Or.Dig_.Tub_.LgI-11-2-ping.png)
Anal canal
The epithelium changes abruptly at the junction of the rectum (simple columnar) with the anal canal (stratified squamous moist). The rectum resembles the rest of the large intestine, having straight intestinal glands with many goblet cells. A more gradual transition of the epithelium occurs between the anal canal and the anus, the latter being lined by a stratified squamous, keratinized epithelium. 100x
![Anus <p>The epithelium changes abruptly at the junction of the rectum (simple columnar) with the anal canal (stratified squamous moist). The rectum resembles the rest of the large intestine, having straight intestinal glands with many goblet cells. A more gradual transition of the epithelium occurs between the anal canal and the anus, the latter being lined by a stratified squamous, keratinized epithelium. 100x</p>](https://digitalhistology.org/wp-content/uploads/2017/10/Or.Dig_.Tub_.LgI-11-3-ping.png)
Anus
The epithelium changes abruptly at the junction of the rectum (simple columnar) with the anal canal (stratified squamous moist). The rectum resembles the rest of the large intestine, having straight intestinal glands with many goblet cells. A more gradual transition of the epithelium occurs between the anal canal and the anus, the latter being lined by a stratified squamous, keratinized epithelium. 100x
![Recto-anal junction <p>The epithelium changes abruptly at the junction of the rectum (simple columnar) with the anal canal (stratified squamous moist). The rectum resembles the rest of the large intestine, having straight intestinal glands with many goblet cells. A more gradual transition of the epithelium occurs between the anal canal and the anus, the latter being lined by a stratified squamous, keratinized epithelium. 100x</p>](https://digitalhistology.org/wp-content/uploads/2017/10/Or.Dig_.Tub_.LgI-11-4-ping.png)
Recto-anal junction
The epithelium changes abruptly at the junction of the rectum (simple columnar) with the anal canal (stratified squamous moist). The rectum resembles the rest of the large intestine, having straight intestinal glands with many goblet cells. A more gradual transition of the epithelium occurs between the anal canal and the anus, the latter being lined by a stratified squamous, keratinized epithelium. 100x
![Region of junction with anus <p>The epithelium changes abruptly at the junction of the rectum (simple columnar) with the anal canal (stratified squamous moist). The rectum resembles the rest of the large intestine, having straight intestinal glands with many goblet cells. A more gradual transition of the epithelium occurs between the anal canal and the anus, the latter being lined by a stratified squamous, keratinized epithelium. 100x</p>](https://digitalhistology.org/wp-content/uploads/2017/10/Or.Dig_.Tub_.LgI-11-5-ping.png)
Region of junction with anus
The epithelium changes abruptly at the junction of the rectum (simple columnar) with the anal canal (stratified squamous moist). The rectum resembles the rest of the large intestine, having straight intestinal glands with many goblet cells. A more gradual transition of the epithelium occurs between the anal canal and the anus, the latter being lined by a stratified squamous, keratinized epithelium. 100x
![Next image > <p>The next image compares these junctional regions at higher magnification.</p>](https://digitalhistology.org/wp-content/uploads/2017/10/Or.Dig_.Tub_.LgI-11-6-ping.png)
Next image >
The next image compares these junctional regions at higher magnification.