![This is blank.](https://digitalhistology.org/wp-content/themes/histology-unified/imgs/trans.png)
Large vein (vena cava)
At higher magnification, the components of the three tunics are evident in this H & E stained cross section. The tunica intima contains smooth muscle in the subendothelial connective tissue beneath the endothelium. The tunica media consists of circularly-arranged muscle. The tunica adventitia contains large amounts of longitudinally-oriented smooth muscle fibers interspersed with connective tissue. 400x
![Tunica intima <p>At higher magnification, the components of the three tunics are evident in this H & E stained cross section. The tunica intima contains smooth muscle in the subendothelial connective tissue beneath the endothelium. The tunica media consists of circularly-arranged muscle. The tunica adventitia contains large amounts of longitudinally-oriented smooth muscle fibers interspersed with connective tissue. 400x</p>](https://digitalhistology.org/wp-content/uploads/2023/10/Or.CV_.V.V-14A-1-ping.png)
Tunica intima
At higher magnification, the components of the three tunics are evident in this H & E stained cross section. The tunica intima contains smooth muscle in the subendothelial connective tissue beneath the endothelium. The tunica media consists of circularly-arranged muscle. The tunica adventitia contains large amounts of longitudinally-oriented smooth muscle fibers interspersed with connective tissue. 400x
![- Endothelium <p>At higher magnification, the components of the three tunics are evident in this H & E stained cross section. The tunica intima contains smooth muscle in the subendothelial connective tissue beneath the endothelium. The tunica media consists of circularly-arranged muscle. The tunica adventitia contains large amounts of longitudinally-oriented smooth muscle fibers interspersed with connective tissue. 400x</p>](https://digitalhistology.org/wp-content/uploads/2023/10/Or.CV_.V.V-14A-2-ping.png)
- Endothelium
At higher magnification, the components of the three tunics are evident in this H & E stained cross section. The tunica intima contains smooth muscle in the subendothelial connective tissue beneath the endothelium. The tunica media consists of circularly-arranged muscle. The tunica adventitia contains large amounts of longitudinally-oriented smooth muscle fibers interspersed with connective tissue. 400x
![- Connective tissue <p>At higher magnification, the components of the three tunics are evident in this H & E stained cross section. The tunica intima contains smooth muscle in the subendothelial connective tissue beneath the endothelium. The tunica media consists of circularly-arranged muscle. The tunica adventitia contains large amounts of longitudinally-oriented smooth muscle fibers interspersed with connective tissue. 400x</p>](https://digitalhistology.org/wp-content/uploads/2023/10/Or.CV_.V.V-14A-3-ping.png)
- Connective tissue
At higher magnification, the components of the three tunics are evident in this H & E stained cross section. The tunica intima contains smooth muscle in the subendothelial connective tissue beneath the endothelium. The tunica media consists of circularly-arranged muscle. The tunica adventitia contains large amounts of longitudinally-oriented smooth muscle fibers interspersed with connective tissue. 400x
![- Smooth muscle fibers <p>At higher magnification, the components of the three tunics are evident in this H & E stained cross section. The tunica intima contains smooth muscle in the subendothelial connective tissue beneath the endothelium. The tunica media consists of circularly-arranged muscle. The tunica adventitia contains large amounts of longitudinally-oriented smooth muscle fibers interspersed with connective tissue. 400x</p>](https://digitalhistology.org/wp-content/uploads/2023/10/Or.CV_.V.V-14A-4-ping.png)
- Smooth muscle fibers
At higher magnification, the components of the three tunics are evident in this H & E stained cross section. The tunica intima contains smooth muscle in the subendothelial connective tissue beneath the endothelium. The tunica media consists of circularly-arranged muscle. The tunica adventitia contains large amounts of longitudinally-oriented smooth muscle fibers interspersed with connective tissue. 400x
![Tunica media <p>At higher magnification, the components of the three tunics are evident in this H & E stained cross section. The tunica intima contains smooth muscle in the subendothelial connective tissue beneath the endothelium. The tunica media consists of circularly-arranged muscle. The tunica adventitia contains large amounts of longitudinally-oriented smooth muscle fibers interspersed with connective tissue. 400x</p>](https://digitalhistology.org/wp-content/uploads/2023/10/Or.CV_.V.V-14A-5-ping.png)
Tunica media
At higher magnification, the components of the three tunics are evident in this H & E stained cross section. The tunica intima contains smooth muscle in the subendothelial connective tissue beneath the endothelium. The tunica media consists of circularly-arranged muscle. The tunica adventitia contains large amounts of longitudinally-oriented smooth muscle fibers interspersed with connective tissue. 400x
![Tunica adventitia <p>At higher magnification, the components of the three tunics are evident in this H & E stained cross section. The tunica intima contains smooth muscle in the subendothelial connective tissue beneath the endothelium. The tunica media consists of circularly-arranged muscle. The tunica adventitia contains large amounts of longitudinally-oriented smooth muscle fibers interspersed with connective tissue. 400x</p>](https://digitalhistology.org/wp-content/uploads/2023/10/Or.CV_.V.V-14A-6-ping.png)
Tunica adventitia
At higher magnification, the components of the three tunics are evident in this H & E stained cross section. The tunica intima contains smooth muscle in the subendothelial connective tissue beneath the endothelium. The tunica media consists of circularly-arranged muscle. The tunica adventitia contains large amounts of longitudinally-oriented smooth muscle fibers interspersed with connective tissue. 400x
![- Smooth muscle fibers <p>At higher magnification, the components of the three tunics are evident in this H & E stained cross section. The tunica intima contains smooth muscle in the subendothelial connective tissue beneath the endothelium. The tunica media consists of circularly-arranged muscle. The tunica adventitia contains large amounts of longitudinally-oriented smooth muscle fibers interspersed with connective tissue. 400x</p>](https://digitalhistology.org/wp-content/uploads/2023/10/Or.CV_.V.V-14A-7-ping.png)
- Smooth muscle fibers
At higher magnification, the components of the three tunics are evident in this H & E stained cross section. The tunica intima contains smooth muscle in the subendothelial connective tissue beneath the endothelium. The tunica media consists of circularly-arranged muscle. The tunica adventitia contains large amounts of longitudinally-oriented smooth muscle fibers interspersed with connective tissue. 400x
![- Connective tissue <p>At higher magnification, the components of the three tunics are evident in this H & E stained cross section. The tunica intima contains smooth muscle in the subendothelial connective tissue beneath the endothelium. The tunica media consists of circularly-arranged muscle. The tunica adventitia contains large amounts of longitudinally-oriented smooth muscle fibers interspersed with connective tissue. 400x</p>](https://digitalhistology.org/wp-content/uploads/2023/10/Or.CV_.V.V-14A-8-ping.png)
- Connective tissue
At higher magnification, the components of the three tunics are evident in this H & E stained cross section. The tunica intima contains smooth muscle in the subendothelial connective tissue beneath the endothelium. The tunica media consists of circularly-arranged muscle. The tunica adventitia contains large amounts of longitudinally-oriented smooth muscle fibers interspersed with connective tissue. 400x
![Image source > <p>This image was taken of a slide from the Drexel University slide collection.</p>](https://digitalhistology.org/wp-content/uploads/2023/10/Drexel-source-ping.png)
Image source >
This image was taken of a slide from the Drexel University slide collection.