Sinusoid
Endothelial cells that form sinusoids have large gaps (discontinuities) between adjacent endothelial cells as well as wide pores (fenestrations) in individual cells. These fenestrations do not have diaphragms. The basal lamina is discontinuous or absent. Shown here in the liver, these modifications allow for direct access of blood plasma to the space beneath the endothelium, into which hepatocytes project microvilli. 30,000x
Sinusoid lumens
Endothelial cells that form sinusoids have large gaps (discontinuities) between adjacent endothelial cells as well as wide pores (fenestrations) in individual cells. These fenestrations do not have diaphragms. The basal lamina is discontinuous or absent. Shown here in the liver, these modifications allow for direct access of blood plasma to the space beneath the endothelium, into which hepatocytes project microvilli. 30,000x
Endothelium
Endothelial cells that form sinusoids have large gaps (discontinuities) between adjacent endothelial cells as well as wide pores (fenestrations) in individual cells. These fenestrations do not have diaphragms. The basal lamina is discontinuous or absent. Shown here in the liver, these modifications allow for direct access of blood plasma to the space beneath the endothelium, into which hepatocytes project microvilli. 30,000x
- Gaps and fenestrations
Endothelial cells that form sinusoids have large gaps (discontinuities) between adjacent endothelial cells as well as wide pores (fenestrations) in individual cells. These fenestrations do not have diaphragms. The basal lamina is discontinuous or absent. Shown here in the liver, these modifications allow for direct access of blood plasma to the space beneath the endothelium, into which hepatocytes project microvilli. 30,000x
Hepatocytes
Endothelial cells that form sinusoids have large gaps (discontinuities) between adjacent endothelial cells as well as wide pores (fenestrations) in individual cells. These fenestrations do not have diaphragms. The basal lamina is discontinuous or absent. Shown here in the liver, these modifications allow for direct access of blood plasma to the space beneath the endothelium, into which hepatocytes project microvilli. 30,000x
- Hepatocyte microvilli
Endothelial cells that form sinusoids have large gaps (discontinuities) between adjacent endothelial cells as well as wide pores (fenestrations) in individual cells. These fenestrations do not have diaphragms. The basal lamina is discontinuous or absent. Shown here in the liver, these modifications allow for direct access of blood plasma to the space beneath the endothelium, into which hepatocytes project microvilli. 30,000x
- Glycogen
Endothelial cells that form sinusoids have large gaps (discontinuities) between adjacent endothelial cells as well as wide pores (fenestrations) in individual cells. These fenestrations do not have diaphragms. The basal lamina is discontinuous or absent. Shown here in the liver, these modifications allow for direct access of blood plasma to the space beneath the endothelium, into which hepatocytes project microvilli. 30,000x
- Mitochondria
Endothelial cells that form sinusoids have large gaps (discontinuities) between adjacent endothelial cells as well as wide pores (fenestrations) in individual cells. These fenestrations do not have diaphragms. The basal lamina is discontinuous or absent. Shown here in the liver, these modifications allow for direct access of blood plasma to the space beneath the endothelium, into which hepatocytes project microvilli. 30,000x