![This is blank.](https://digitalhistology.org/wp-content/themes/histology-unified/imgs/trans.png)
Rough endoplasmic reticulum
At the EM level, large accumulations of RER can be seen at the base of the cell. The nucleus is also in the cell base, while secretory granules are in the apex, waiting release into the duct of the gland. The segregation of the RER and secretory granules results in cell polarity, indicating the cell is making protein for exocrine secretion. Pancreas 4000x
![Cell outline <p>At the EM level, large accumulations of RER can be seen at the base of the cell. The nucleus is also in the cell base, while secretory granules are in the apex, waiting release into the duct of the gland. The segregation of the RER and secretory granules results in cell polarity, indicating the cell is making protein for exocrine secretion. Pancreas 4000x</p>](https://digitalhistology.org/wp-content/uploads/2017/05/C.S.ER-3-4-ping.png)
Cell outline
At the EM level, large accumulations of RER can be seen at the base of the cell. The nucleus is also in the cell base, while secretory granules are in the apex, waiting release into the duct of the gland. The segregation of the RER and secretory granules results in cell polarity, indicating the cell is making protein for exocrine secretion. Pancreas 4000x
![- Nucleus <p>At the EM level, large accumulations of RER can be seen at the base of the cell. The nucleus is also in the cell base, while secretory granules are in the apex, waiting release into the duct of the gland. The segregation of the RER and secretory granules results in cell polarity, indicating the cell is making protein for exocrine secretion. Pancreas 4000x</p>](https://digitalhistology.org/wp-content/uploads/2017/05/C.S.ER-3-2-ping.png)
- Nucleus
At the EM level, large accumulations of RER can be seen at the base of the cell. The nucleus is also in the cell base, while secretory granules are in the apex, waiting release into the duct of the gland. The segregation of the RER and secretory granules results in cell polarity, indicating the cell is making protein for exocrine secretion. Pancreas 4000x
![- RER <p>At the EM level, large accumulations of RER can be seen at the base of the cell. The nucleus is also in the cell base, while secretory granules are in the apex, waiting release into the duct of the gland. The segregation of the RER and secretory granules results in cell polarity, indicating the cell is making protein for exocrine secretion. Pancreas 4000x</p>](https://digitalhistology.org/wp-content/uploads/2017/05/C.S.ER-3-1-ping.png)
- RER
At the EM level, large accumulations of RER can be seen at the base of the cell. The nucleus is also in the cell base, while secretory granules are in the apex, waiting release into the duct of the gland. The segregation of the RER and secretory granules results in cell polarity, indicating the cell is making protein for exocrine secretion. Pancreas 4000x
![- Secretory granules <p>At the EM level, large accumulations of RER can be seen at the base of the cell. The nucleus is also in the cell base, while secretory granules are in the apex, waiting release into the duct of the gland. The segregation of the RER and secretory granules results in cell polarity, indicating the cell is making protein for exocrine secretion. Pancreas 4000x</p>](https://digitalhistology.org/wp-content/uploads/2017/05/C.S.ER-3-3-ping.png)
- Secretory granules
At the EM level, large accumulations of RER can be seen at the base of the cell. The nucleus is also in the cell base, while secretory granules are in the apex, waiting release into the duct of the gland. The segregation of the RER and secretory granules results in cell polarity, indicating the cell is making protein for exocrine secretion. Pancreas 4000x
![Lumen of duct <p>At the EM level, large accumulations of RER can be seen at the base of the cell. The nucleus is also in the cell base, while secretory granules are in the apex, waiting release into the duct of the gland. The segregation of the RER and secretory granules results in cell polarity, indicating the cell is making protein for exocrine secretion. Pancreas 4000x</p>](https://digitalhistology.org/wp-content/uploads/2017/05/C.S.ER-3-5-ping.png)
Lumen of duct
At the EM level, large accumulations of RER can be seen at the base of the cell. The nucleus is also in the cell base, while secretory granules are in the apex, waiting release into the duct of the gland. The segregation of the RER and secretory granules results in cell polarity, indicating the cell is making protein for exocrine secretion. Pancreas 4000x