Spleen
This image of the white pulp in longitudinal view shows the relationship between the white pulp and its blood supply. Branches of the splenic artery travel in the trabeculae and enter the white pulp as the central artery or central arteriole. The central arteriole is surrounded by a cylindrical sleeve of lymphocytes called the periarterial lymphoid sheath or PALS, and consists mostly of T lymphocytes.
White pulp
This image of the white pulp in longitudinal view shows the relationship between the white pulp and its blood supply. Branches of the splenic artery travel in the trabeculae and enter the white pulp as the central artery or central arteriole. The central arteriole is surrounded by a cylindrical sleeve of lymphocytes called the periarterial lymphoid sheath or PALS, and consists mostly of T lymphocytes.
Red pulp
This image of the white pulp in longitudinal view shows the relationship between the white pulp and its blood supply. Branches of the splenic artery travel in the trabeculae and enter the white pulp as the central artery or central arteriole. The central arteriole is surrounded by a cylindrical sleeve of lymphocytes called the periarterial lymphoid sheath or PALS, and consists mostly of T lymphocytes.
Central arteriole
This image of the white pulp in longitudinal view shows the relationship between the white pulp and its blood supply. Branches of the splenic artery travel in the trabeculae and enter the white pulp as the central artery or central arteriole. The central arteriole is surrounded by a cylindrical sleeve of lymphocytes called the periarterial lymphoid sheath or PALS, and consists mostly of T lymphocytes.
Periarterial lymphoid sheath (PALS)
Along the course of the PALS, nodules develop within the PALS in response to B-cell activation. These nodules resemble secondary nodules seen in other lymphatic tissues, including the presence of pale-staining, germinal centers resulting from B cell proliferation. Their growth displaces the central arteriole to an eccentric position. The darker staining, T-dependent region of the PALS surrounds the germinal center.
Lymphoid nodules
Along the course of the PALS, nodules develop within the PALS in response to B-cell activation. These nodules resemble secondary nodules seen in other lymphatic tissues, including the presence of pale-staining, germinal centers resulting from B cell proliferation. Their growth displaces the central arteriole to an eccentric position. The darker staining, T-dependent region of the PALS surrounds the germinal center.
Area shown in next image
This area is shown at higher magnification in the next image.
Image source >
Image taken of a slide from the University of Michigan collection.
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