Secretory units
This composite image compares the structure of an acinus (left) and a tubule (right). Pancreas 1000x (R), Sublingual salivary gland 600x (L)
Acinus >
An acinus resembles a grapefruit cut in half, with each grapefruit segment representing an individual cell. The RER and nucleus are basally located in the cells, while their secretory granules are present in the apical regions. At the center of the acinus is a narrow lumen. Acinar secretions are watery or serous which enter the small central lumen.
- Gland cells
An acinus resembles a grapefruit cut in half, with each grapefruit segment representing an individual cell. The RER and nucleus are basally located in the cells, while their secretory granules are present in the apical regions. At the center of the acinus is a narrow lumen. Acinar secretions are watery or serous which enter the small central lumen.
- RER
An acinus resembles a grapefruit cut in half, with each grapefruit segment representing an individual cell. The RER and nucleus are basally located in the cells, while their secretory granules are present in the apical regions. At the center of the acinus is a narrow lumen. Acinar secretions are watery or serous which enter the small central lumen.
- Secretory granules (serous)
An acinus resembles a grapefruit cut in half, with each grapefruit segment representing an individual cell. The RER and nucleus are basally located in the cells, while their secretory granules are present in the apical regions. At the center of the acinus is a narrow lumen. Acinar secretions are watery or serous which enter the small central lumen.
- Lumen
An acinus resembles a grapefruit cut in half, with each grapefruit segment representing an individual cell. The RER and nucleus are basally located in the cells, while their secretory granules are present in the apical regions. At the center of the acinus is a narrow lumen. Acinar secretions are watery or serous which enter the small central lumen.
Tubules >
Tubules, as the name indicates, are linear secretory units lined by cuboidal to columnar cells. A number of tubules in longitudinal and cross section are visible in the image. Most tubules secrete mucus and the apical region appears frothy or clear because the mucus is easily extracted during tissue processing. The nuclei are basally located and compressed by the mass of mucus above them. Tubules have a wide lumen to accommodate the thick, mucus secretion.
- Tubule cells
Tubules, as the name indicates, are linear secretory units lined by cuboidal to columnar cells. A number of tubules in longitudinal and cross section are visible in the image. Most tubules secrete mucus and the apical region appears frothy or clear because the mucus is easily extracted during tissue processing. The nuclei are basally located and compressed by the mass of mucus above them. Tubules have a wide lumen to accommodate the thick, mucus secretion.
- Nuclei
Tubules, as the name indicates, are linear secretory units lined by cuboidal to columnar cells. A number of tubules in longitudinal and cross section are visible in the image. Most tubules secrete mucus and the apical region appears frothy or clear because the mucus is easily extracted during tissue processing. The nuclei are basally located and compressed by the mass of mucus above them. Tubules have a wide lumen to accommodate the thick, mucus secretion.
- Secretory granules (mucus)
Tubules, as the name indicates, are linear secretory units lined by cuboidal to columnar cells. A number of tubules in longitudinal and cross section are visible in the image. Most tubules secrete mucus and the apical region appears frothy or clear because the mucus is easily extracted during tissue processing. The nuclei are basally located and compressed by the mass of mucus above them. Tubules have a wide lumen to accommodate the thick, mucus secretion.
- Lumens
Tubules, as the name indicates, are linear secretory units lined by cuboidal to columnar cells. A number of tubules in longitudinal and cross section are visible in the image. Most tubules secrete mucus and the apical region appears frothy or clear because the mucus is easily extracted during tissue processing. The nuclei are basally located and compressed by the mass of mucus above them. Tubules have a wide lumen to accommodate the thick, mucus secretion.
Polarity >
Polarity is a feature of cells in which their organelles are distributed asymmetrically in the cytoplasm. This stable distribution of organelles reflects the differing functions performed in these areas. The secretory products, e.g., enzymes or mucus, are synthesized basally in the RER, packaged into secretory granules that are stored in the apical region of the cells for later release. Polarity is a characteristic feature of exocrine gland cells.