Cilia and basal bodies
The structural core of a cilum is formed by microtubules arranged in a highly conserved pattern called the axoneme. The basal body also consists of microtubules arranged in a complex located at the base of each cilium. These electron micrographs the compare the structures of cilia and basal bodies in longitudinal (left) and cross-sectional planes (right). 20,000x (left), 150,000x (right)
Cilia section plane >
The cross sectional image of cilia on the right corresponds to the level indicated by the red arrow.
Cilia
The cross sectional image of cilia on the right corresponds to the level indicated by the red arrow.
- Axoneme >
The axoneme forms the central core of a cilium and consists of nine pairs of microtubules (doublets) surrounding two central, individual microtubules (9 + 2 arrangement). The doublets arise from microtubules in the basal body, while the central pair is assembled de novo at the base of the cilium. Molecular interactions between the microtubule doublets produce the whip-like motion of the cilium while the central pair serves to regulate ciliary motility. The axoneme extends the length of the cilium and a similar structure is present in flagella.
- Doublets
The axoneme forms the central core of a cilium and consists of nine pairs of microtubules (doublets) surrounding two central, individual microtubules (9 + 2 arrangement). The doublets arise from microtubules in the basal body, while the central pair is assembled de novo at the base of the cilium. Molecular interactions between the microtubule doublets produce the whip-like motion of the cilium while the central pair serves to regulate ciliary motility. The axoneme extends the length of the cilium and a similar structure is present in flagella.
- Central pair
The axoneme forms the central core of a cilium and consists of nine pairs of microtubules (doublets) surrounding two central, individual microtubules (9 + 2 arrangement). The doublets arise from microtubules in the basal body, while the central pair is assembled de novo at the base of the cilium. Molecular interactions between the microtubule doublets produce the whip-like motion of the cilium while the central pair serves to regulate ciliary motility. The axoneme extends the length of the cilium and a similar structure is present in flagella.
- Plasma membrane
The axoneme forms the central core of a cilium and consists of nine pairs of microtubules (doublets) surrounding two central, individual microtubules (9 + 2 arrangement). The doublets arise from microtubules in the basal body, while the central pair is assembled de novo at the base of the cilium. Molecular interactions between the microtubule doublets produce the whip-like motion of the cilium while the central pair serves to regulate ciliary motility. The axoneme extends the length of the cilium and a similar structure is present in flagella.
Microvilli >
Ciliated cells also extend microvilli which are much shorter than cilia and have a core of microfilaments rather than microtubules.
Basal body section plane >
The cross sectional image of basal bodies on the right corresponds to the level indicated by the red arrow.
Basal bodies >
Basal bodies are short barrel-shaped structures located at the base of each cilium. They are composed of 9 sets of microtubule triplets arranged in a hollow cylinder with no central microtubules (9 + 0) arrangement. The microtubule doublets of the cilium arise from the basal body. Basal bodies are structurally identical to centrioles.
- Triplets
Basal bodies are short barrel-shaped structures located at the base of each cilium. They are composed of 9 sets of microtubule triplets arranged in a hollow cylinder with no central microtubules (9 + 0) arrangement. The microtubule doublets of the cilium arise from the basal body. Basal bodies are structurally identical to centrioles.
Image source >
The images in the right panels were generated by Dr. Johannes A. G. Rhodin, “An Atlas of Histology” (Oxford Press, 1974) and maintained in the University of Michigan collection.