Receptors
Pacinian corpuscles are encapsulated sensory receptors located in connective tissues throughout the body, but are most numerous in the deep layers of the skin. Pacinian corpuscles consist of a centrally located axon surrounded by multiple layers of endoneurial and Schwann cells. These receptors respond to pressure and vibration and can be up to 1 mm in diameter. 400x
Pacinian corpuscle >
Pacinian corpuscles consist of concentric layers of endoneurial cells and Schwann cells, which surround a central, unmyelinated axon. When cut in cross section, the internal structure of the receptor resembles a sliced onion, and the lymph-like fluid between the lamellae allows the receptor to adapt and respond to stimuli for deep pressure and vibration.
Axon
Pacinian corpuscles consist of concentric layers of endoneurial cells and Schwann cells, which surround a central, unmyelinated axon. When cut in cross section, the internal structure of the receptor resembles a sliced onion, and the lymph-like fluid between the lamellae allows the receptor to adapt and respond to stimuli for deep pressure and vibration.
Endoneurial and Schwann cells
Pacinian corpuscles consist of concentric layers of endoneurial cells and Schwann cells, which surround a central, unmyelinated axon. When cut in cross section, the internal structure of the receptor resembles a sliced onion, and the lymph-like fluid between the lamellae allows the receptor to adapt and respond to stimuli for deep pressure and vibration.