Stratum corneum - Thin skin
There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x
Epidermis
There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x
Stratum basale
There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x
Stratum spinosum
There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x
Stratum granulosum
There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x
Stratum corneum
There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x
- Squames
There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x
Dermis
There is normally an abrupt transition between the stratum granulosum and the stratum corneum. Stratum corneum consists of non-living keratinized cells or squames that consists of a cornified cell envelope surrounding a matrix of aggregated tonofibrils. These cells are continuously shed from the surface of the epidermis and are replenished through the upward migration and ongoing keratinization of epidermal keratinocytes. The keratin matrix accounts for the strong eosinophilic staining seen in these cells. 400x
Image source >
Image taken of a slide in the University of Iowa slide collection.